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DIABETES (also see Women’s Health)


Cohort Study of Pioglitazone and Bladder Cancer in Patients With Diabetes Mellitus

Division of Research Site Principal Investigator: Assiamira Ferrara, MD, PhD
Primary Source of
Funding: Takeda Pharmaceuticals North America
Title describes study.


Do Free Glucose Test Strips Increase Self-Monitoring?

Division of Research Principal Investigator: Andrew J. Karter, PhD
Primary Source of
Funding: National Institute of Diabetes and Digestive and Kidney Diseases
Description:
This study quantifies the impact of providing free self-monitoring of blood glucose (SMBG) strips to diabetic patients in terms of: 1) individual-level utilization and glycemic control, with special attention to disparities across ethnicity, socioeconomic status, and disease severity, 2) population-level impact in terms of changes in glycemic control attributable to changes in adherence to recommended SMBG practice, and 3) the cost-effectiveness of providing free SMBG strips.


Educational Disparities in Diabetes Complications

Division of Research Principal Investigator: Andrew J. Karter, PhD
Primary Source of
Funding: National Institute of Diabetes and Digestive and Kidney Diseases
Description:
This study explored the link between education, as well as other socioeconomic indicators, and the incidence of diabetic complications, and identifies explanatory factors in a large, ethnically diverse, and well-defined population of diabetes mellitus patients.


Epidemiology of Glycemia Inflammation & Cognition

Division of Research Principal Investigator: Rachel Whitmer, PhD
Primary Source of Funding:
National Institute of Diabetes & Digestive & Kidney Diseases
Description:
This study will examine whether levels of glycemia, insulinemia, and inflammatory factors are predictive of cognitive impairment across the entire range of glucose tolerance.


Ethnic Disparities in Diabetes Complications

Division of Research Principal Investigator: Andrew J. Karter, PhD
Primary Source of
Funding: National Institute of Diabetes and Digestive and Kidney Diseases
Description:
This study seeks to evaluate ethnic differences in the incidence and antecedents of diabetic complications in a large population of African Americans, Asians, Caucasians, Filipinos and Latinos, and examine health services and epidemiologic aspects of diabetic complications including myocardial infarction, stroke, congestive heart failure, end-stage renal disease, lower-extremity amputation and proliferative retinopathy.


Glycemic Response-to-Therapy

Division of Research Principal Investigator: Andrew J. Karter, PhD
Primary Source of Funding:
Novartis Foundation
Description:
This one year study of the real-world effectiveness of diabetes therapies investigates whether the size of effect (e.g., improvement in HbA1c) afforded by initiating new diabetes therapies varies across demographic and risk categories in patients with diabetes.


Hypertension, Dyslipidemia, and Diabetes Mellitus: Prevalence, Co-occurrence, Treatment and Control in a Large Managed Care Population

Division of Research Principal Investigator: Joe V. Selby, MD, MPH
Primary Source of
Funding: Pfizer Inc.
Description:
This study evaluates the prevalence, co-occurrence, and treatment patterns of diabetes mellitus, hypertension, and dyslipidemia.


Incidence of Lung Cancer, Chronic Obstructive Pulmonary Disease, Pneumonia and Pulmonary Fibrosis Among Persons with and Without Diabetes Mellitus

Division of Research Principal Investigator: Assiamira Ferrara, MD, PhD
Primary Source of
Funding: Pfizer, Inc.
Description:
This study seeks to estimate the incidence of lung cancer in a cohort of diabetic patients, to estimate the risk and incidence of lung cancer in diabetic patients within different treatment groups, and to estimate the risk of lung cancer in diabetic patients within treatment groups compared to that in a non-diabetic population.


Increasing the Evidence Base for Retinopathy Screening Guidelines

Division of Research Principal Investigator: Joe V. Selby, MD, MPH
Primary Source of
Funding: American Diabetes Association
Description:
This study explores clinical outcomes following negative retinal screening examinations and exams showing only minimal retinopathy in diabetic patients, with the goal of identifying optimal screening intervals following these examinations.


Medication Use and Glucose Control Among Type 2 Diabetics

Division of Research Principal Investigator: Assiamira Ferrara, MD, PhD
Primary Source of
Funding: SmithKline Beecham
Description:
This study seeks to determine the extent and nature of polypharmacy, to list drug interactions that should be monitored, and to study whether glycemic control varies by medication use.


Measuring Clinical Benefit and Value of Diabetes Care

Division of Research Principal Investigator: Joe V. Selby, MD, MPH
Primary Source of
Funding: Agency for Healthcare Research and Quality
Description:
This is the first phase of a project that seeks to improve current methods of measuring and comparing the performance of disease management programs for diabetes.


Natural History of Glycemic Control Among Patients with Diabetes

Division of Research Principal Investigator: Andrew J. Karter, PhD
Primary Source of
Funding: Pfizer Incorporated
Description:
This observational study examines how glycemic control in diabetic patients varies by treatment regimen, and how glycemic control changes over time.


Probability of Treating-to-Target: Type 2 Diabetes Patients from the Northern California Kaiser Permanente Diabetes Registry Starting New Anti-Hyperglycemic Therapies

Division of Research Principal Investigator: Andrew Karter, PhD
Primary Source of
Funding: Pfizer Incorporated
Description:
This epidemiologic study evaluates the proportion of patients with Type 2 diabetes who are switched to new diabetes therapies and reach and maintain glycemic control targets.


Prospective Study of Childbearing and Correlates of Insulin Resistance in Nondiabetic Women

Division of Research Principal Investigator: Erica Gunderson, PhD
Primary Source of Funding:
American Diabetes Association
Description:
This study will evaluate whether childbearing is associated with more unfavorable changes in correlates of insulin sensitivity and inflammatory markers controlling for pregravid risk status and GDM status.


The Epidemiology of Anemia in Patients With Diabetes

Division of Research Principal Investigator: Andrew Karter, PhD
Primary Source of
Funding: Kaiser Permanente Community Benefit Programs
Description:
This cohort and nested case-control study characterizes the testing, prevalence, predictors, and treatment of clinically-recognized anemia in a large, ethnically-diverse, well-defined population of adult diabetes patients.


Translational Research Center for Diabetes Control Within Managed Care I and II

Division of Research Principal Investigator: Joe V. Selby, MD, MPH
Primary Source of
Funding: Centers for Disease Control and Prevention
Description:
This project describes current levels of diabetes care, analyzes system-level determinants of level of care, studies health care professional and patient-level factors that influence the effectiveness of care, develops new quality indicators, and identifies and evaluates the aim to improve levels of screening and risk management for patients with diabetes.


Specialized Centers of Research: Diabetes: Reproductive/Hormonal Risk Factors II

Division of Research Site Principal Investigator: Stephen K. Van Den Eeden, PhD
Primary Source of
Funding: National Institute of Diabetes, Digestive and Kidney Diseases
Description:
This study investigates the role of diabetes in incontinence among women as part of the University of California, San Francisco, Division of Research investigations under the Specialized Centers of Research (SCOR) in Women's Health.

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