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CANCER


A Nested Case-Control Study of NHL, Serum Levels of Organochlorines and Epsiten-Barr Virus Serology

Division of Research Principal Investigator: Lisa Herrinton, PhD
Primary Source of
Funding: National Cancer Institute
Description:
This project will assess the risk for NHL associated with serum levels of PCB congeners and EBV seropositivity; to carry out a pilot study for analysis of polymorphisms in immune function.


Accuracy of Physical Activity Measures in Cancer Studies

Division of Research Principal Investigator: Barbara Sternfeld, PhD
Primary Source of
Funding: National Cancer Institute/NIH/DHHS
Description:
Identify and quantify the measurement error associated with two self-administered physical activity (PA) questionnaires used to assess recent activity in two ongoing cancer cohort studies (Life After Cancer Epidemiology, funded by NCI, and the California Men’s Health Study, funded by the California Cancer Research Program).


Association of PPAR Gamma Ligands and Colonic Neoplasia

Division of Research Site Principal Investigator: Laurel Habel, PhD
Primary Source of
Funding: National Cancer Institute
Description:
This study seeks to assess the potential association between a new class of diabetic drugs, thiazolidinediones (TZDs), and risk of colonic neoplasia among a population of individuals with type 2 diabetes mellitus.


Biomarkers of Lung Cancer Susceptibility in Minorities

Division of Research Principal Investigator: Charles Quesenberry, PhD
Primary Source of Funding
: National Institute of Environmental Health Sciences
Description:
This study focuses on African-Americans who bear a disproportionate burden of lung cancer and Latinos who have very low rates; it will explore candidate susceptibility gene loci never before studied in minorities.


California Men’s Study (CMS): A Prospective Cohort Study for Prostate Cancer

Division of Research Principal Investigator: Bette J. Caan, DrPH
Primary Source of
Funding: California Department of Health Services
Description
: This prospective study of 100,000 men between the ages of 45 and 69 examines behavioral and demographic characteristics related to incident prostate cancer among men of different ethnicities.


Cancer Care Outcomes Research and Surveillance (CanCORS)

Division of Research Site Principal Investigator: Lisa Herrinton, PhD
Primary Source of
Funding: National Cancer Institute
Description:
This award supports population based research in the areas of access to care, patterns of care, and prognosis of lung and colorectal cancer.


Cancer Incidence Among Patients Diagnosed with Hep. B

Division of Research Principal Investigator: Charles Quesenberry, PhD
Primary Source of
Funding: Kaiser Foundation Research Institute
Description:
Quantify the incidence of cancer among patients with hepatitis B and comparison cohorts of patients.


Cancer Research Network Across Health Care Systems (CRN2) – Infrastructure

Division of Research Site Principal Investigator: Lisa Herrinton, PhD
Primary Source of
Funding: National Cancer Institute
Description:
The Cancer Research Network is a consortium of 10 integrated delivery systems that are funded by the National Cancer Institute to conduct research into the epidemiology, care, and outcomes of cancer.


Cancer Research Network Across Health Care Systems, Project 3: Effectiveness of Breast Cancer Screening and Prophylactic Mastectomy

Division of Research Principal Investigator: Lisa Herrinton, PhD
Primary Source of
Funding: National Cancer Institute
Description:
Title describes study.


Cancer Surveillance in HMO Administrative Data

Division of Research Site Principal Investigator: Charles Quesenberry, PhD
Primary Source of
Funding: National Cancer Institute
Description
: This study identifies the existence and extent of biases associated with integrated delivery system electronic and claims-type encounter data when used to characterize patterns of care and to analyze the relationship between treatment and outcomes of breast and cervical cancers.


Cohort Study of Risk of Lymphoproliferative Cancer Among Rheumatoid Arthritis (RA) Patients, by Severity of RA

Division of Research Principal Investigator: Lisa Herrinton, PhD
Primary Source of
Funding: Wyeth Pharmaceuticals
Description:
This study estimates the standardized incidence ratio for lymphoproliferative cancers (lymphomas, myeloma, and leukemia) among RA patients with severe disease.


CRN II: Cancer Research Network Infrastructure

Division of Research Principal Investigator: Lisa Herrinton, PhD
Primary Source of
Funding: National Cancer Institute/NIH/DHHS
Description
: Build a population laboratory for cancer research in HMO populations.


Evaluation of Hospice Referral and Palliative Care for Ovarian Cancer in the Managed Care Environment

Division of Research Site Principal Investigator: Lisa Herrinton, PhD
Primary Source of
Funding: Centers for Disease Control and Prevention
Description:
This study examines end-of-life care for women with ovarian cancer when the goal of treatment shifts from quantity of life to sustaining quality of life and symptom relief.


Geographic and Temporal Variation in Prevalence of Established Breast Cancer Risk Factors, 1988-1999.

Division of Research Site Principal Investigator: Lawrence Kushi, ScD
Primary Source of
Funding: NCCC


Long-Term, Prospective, Observational Study of the Risk of Cancer Among Pantoprazole (Protonix®) Users

Site Principal Investigator: Doug Corley, MD, PhD, MPH
Primary Source of
Funding: Wyeth-Lederle
Description:
Finding out if there is an increased risk of cancer with pantoprazole (Protonix®) relative to the other proton pump inhibitors.


Multi-Center Study of Pancreatic Cancer Etiology

Division of Research Site Principal Investigator: Stephen Van Den Eeden, PhD
Primary Source of
Funding: National Cancer Institute/NIH/DHHS
Description
: Multi-site study that examines behavioral and environmental risk factors for pancreatic cancer, and creates a biorepository for future genetic studies.


Multi-Site Study of Pancreatic Cancer Etiolgy

Division of Research Site Principal Investigator: Stephen Van Den Eeden, PhD
Primary Source of
Funding: National Cancer Institute
Description:
This multi-site study examines behavioral and environmental risk factors for pancreatic cancer, and creates a biorepository for future genetic studies.


Epidemiology of Marginal Zone Lymphoma

Division of Research Principal Investigator: Lisa Herrinton, PhD
Primary Source of
Funding: National Cancer Institute
This study examines inflammatory conditions in relation to the risk of marginal zone lymphoma and studies the course of disease and variation in care.


Insulin Resistance and Adenomas of the Colorectum (IRAsC)

Division of Research Principal Investigator: Theodore R. Levin, MD
Primary Source of
Funding: National Cancer Institute
Description:
This study tests the hypothesis that colorectal neoplasia risk is increased substantially by factors related to insulin resistance and examines the biologic mechanisms whereby that risk is increased.


Paternal Exposures and Sporadic Retinoblastoma

Division of Research Site Principal Investigator: Lawrence Kushi, ScD
Primary Source of
Funding: National Cancer Institute
Description:
This case-control study examines various paternal environmental exposures including diet and risk of a rare childhood cancer, retinoblastoma, with a strong genetic basis, but otherwise unknown etiology.


Pharmaceuticals and Cancer

Division of Research Principal Investigator: Laurel Habel, PhD
Primary Source of
Funding: National Cancer Institute
Description
: This study examines whether the 200 most commonly prescribed medications are associated with lower or higher rates of cancer and evaluates whether these associations deserve further study.


Pharmaceuticals and Cancer

Division of Research Principal Investigator: Laurel Habel, PhD
Primary Source of
Funding: National Cancer Institute/NIH/DHHS
Description:
Study potential cancer-drug associations.


Selenium and Vitamin E Cancer Prevention Trial (SELECT)

Division of Research Principal Investigator: Carol Somkin,, PhD
Primary Source of
Funding: National Cancer Institute/NIH/DHHS
Description:
Provide access to the SELECT Trial to male members of California Kaiser Permanente.


Systematic Literature Review on Food, Nutrition, Physical Activity and the Prevention of Endometrial Cancer

Division of Research Principal Investigator: Lawrence Kushi, ScD
Primary Source of
Funding: World Cancer Research Fund International
Description:
This Contract supports systematic literature reviews on the topic noted above to support the upcoming 2006 publication on Food, Nutrition, Physical Activity and the Prevention of Cancer.

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