Michael J. Silverberg, PhD, MPH

Michael J. Silverberg, PhD, MPH, has been a Research Scientist at the Division of Research (DOR), Kaiser Permanente Northern California, since 2004. Dr. Silverberg received his doctorate in Epidemiology from the Johns Hopkins University, Bloomberg School of Public Health, in 2001. He received his MPH in Epidemiology from the University of California at Los Angeles, California, School of Public Health, in 1997. Prior to joining DOR, Dr. Silverberg was an Assistant Research Professor in the Department of Epidemiology at Johns Hopkins University. At DOR, Dr. Silverberg is developing HIV/AIDS research initiatives in conjunction with the Garfield Memorial Fund sponsored HIV Initiative.

Dr. Silverberg’s primary research interests include comorbidities associated with HIV infection and antiretroviral therapy (ART) use, including malignancies and cardiovascular disease; racial/ethnic differences in HIV treatment and outcome; analytical methods for longitudinal cohort and registry-based studies; and co-infection with HIV and human papillomavirus (HPV).

Current Position:

Research Scientist, Division of Research, Kaiser Permanente Northern California

Primary Research Interests:

	Malignancies in HIV patients
	HIV and cardiovascular complications.
	Racial/ethnic differences in HIV care
	Infectious disease epidemiology

Current Research Projects:

	HIV Infection, Antiretroviral Therapy, Cancer Incidence and Progression
	Adverse Event Surveillance Among HIV Patients Treated With Antiretrovirals
	Long-term Opioid Management of Chronic Pain in HIV patients
	Patient Portal to Support Treatment Adherence in HIV Patients
	North American AIDS Cohort Collaboration on Research and Design
	Epidemiology and Natural History of Herpes Zoster in Cancer Patients

Selected Publications:

	Grant LA, Silverberg MJ, Palacio H, Minkoff H, Anastos K, Young MA, Nowicki M, Kovacs A, Cohen M, Muñoz A. Discontinuation of potent antiretroviral therapy: predictive value of and impact on CD4 cell counts and HIV RNA levels. AIDS 2001;15:2101-8.
	Silverberg MJ, Grant LA, Muñoz A, Anastos K, Burk RD, Cu-Uvin S, Duerr A, Greenblatt RM, Klein RS, Massad S, Minkoff H, Muderspach L, Palefsky J, Piessens E, Schuman P, Watts H, Shah KV. The impact of HIV infection and immunodeficiency on human papillomavirus Type 6 or 11 infection and on genital warts. Sex Transm Dis 2002;29:427-35.
	Silverberg MJ, Brundage JF, Rubertone MV. Timing and completeness of routine testing for antibodies to human immunodeficiency virus, Type 1, among active duty members of the U.S. Armed Forces. Mil Med 2003;168:160-4.
	Silverberg MJ, Thorsen P, Lindeberg H, Grant LA, Shah KV. Condyloma in pregnancy is strongly predictive of juvenile onset recurrent respiratory papillomatosis. Obstet Gynecol 2003;101:645-52.
	Silverberg MJ, Smith MW, Chmiel JS, Detels R, Margolick JB, Rinaldo CR, O’Brien SJ, Muñoz A. Fraction of AIDS cases prevented by the interactions of identified restriction gene variants. Am J Epidem 2004;159:232-41.
	Massad LS, Silverberg MJ, Springer G, Minkoff H, Hessol N, Palefsky JM, Strickler HD, Levine AM, Sacks HS, Moxley M, Watts H. Effect of antiretroviral therapy on the incidence of genital warts and vulvar neoplasia among women with himan immunodeficiency virus. Am J Obstet Gynecol 2004;190:1241-8.
	Silverberg MJ, Thorsen, P, Grant LA, Lindeberg H, Shah KV. Clinical course of recurrent respiratory papillomatosis in Danish children. Arch Otol Head Neck Surg 2004;130:711-6..
	Silverberg MJ, Gore ME, French AL, Gandhi M, Glesby MJ, Kovacs A, Wilson TE, Young MA, Gange SJ. Prevalence of clinical symptoms associated with highly active antiretroviral therapy in the Women’s Interagency HIV Study. Clin Infect Dis 2004;39:717-24.
	Wiley DJ, Harper DM, Elashoff D, Silverberg MJ, Kaestle C, Cook RL, Heilemann M, Johnson L. How condom use, number of receptive anal intercourse partners and history of external genital warts predict risk for external anal warts. Int J STD AIDS 2005;16:203-11.
	Harris TG, Burk RD, Palefsky JM, Massad LS, Bang JY, Anastos K, Minkoff H, Hall CB, Bacon MC, Levine AM, Watts DH, Silverberg MJ, Xue X, Melnick SL, Strickler HD. Incidence of cervical squamous intraepithelial lesions associated with HIV serostatus, CD4 cell counts, and human papillomavirus test results. JAMA 2005;293:1471-6.
	Strickler HD, Burk RD, Fazzari M, Anastos K, Minkoff H, Massad LS, Hall C, Bacon M, Levine AM, Watts DH, Silverberg MJ, Xue X, Schlecht NF, Melnick S, Palefsky JM.. Human Papillomavirus (HPV) Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive women. J Natl Cancer Inst. 2005;97:577-86.
	Silverberg MJ, Schneider MF, Silver B, Anastos KM, Burk RD, Minkoff H, Palefsky J, Levine AM, Viscidi RP. Serological detection of human papillomavirus type 16 infection in human immunodeficiency virus (HIV)-positive and high-risk HIV-negative women. Clin Vaccine Immunol 2006;13:511-9.
	Silverberg MJ, Wegner SA, Milazzo MJ, McKaig RG, Williams CF, Agan BK, Armstrong AW, Gange SJ, Hawkes C, O’Connell RJ, Wallace MR, Ahuja SK, Dolan MJ. Effectiveness of highly-active antiretroviral therapy by race/ethnicity. AIDS 2006;20:1531-8.
	Horberg MA, Hurley LB, Silverberg MJ, Kinsman CJ, Quesenberry CP. Effect of clinical pharmacists on utilization and clinical response to antiretroviral therapy. JAIDS 2007;44:531-9.
	Silverberg MJ, Leyden W, Horberg M, Delorenze J, Klein D, Quesenberry C. Older age and the response to and tolerability of antiretroviral therapy. Arch Intern Med 2007;167:684-91.
	Silverberg MJ, Neuhaus J, Bower M, Gey D, Hatzakis A, Henry K, Hidalgo J, Lourtau L, Neaton JD, Tambussi G, Abrams DI. Risk of cancers during interrupted antiretroviral therapy in the SMART study. AIDS 2007;21:1957-63.
	Silverberg MJ, Abrams D. AIDS-defining and non-AIDS-defining malignancies: cancer occurrence in the antiretroviral therapy era. Curr Opin Oncol 2007;19:446-51.
	Ostrow DG, Silverberg MJ, Cook RL, Chmiel JS, Johnson L, Li X, Jacobson LP. Prospective study of attitudinal and relationship predictors of sexual risk in the Multicenter AIDS Cohort Study. AIDS Behav 2008;12(1):127-38.
	Horberg MA, Silverberg MJ, Hurley LB, et al. Effects of Depression and SSRI Use on Adherence to HAART and on Clinical Outcomes in HIV-Infected Patients. J Acquir Immune Defic Syndr 2008;47(3):384-90.
	Horberg M, Silverberg MJ, Hurley L, et. al. Influence of prior antiretroviral experience on adherence and responses to new highly active antiretroviral therapy regimens. AIDS Patient Care STDS 2008 Mar; epub ahead of print.
	Baker JV, Peng G, Rapkin J, Abrams DI, Silverberg MJ, et. al. CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection. AIDS, in press.
	Von Korff M, Saunders K, Ray GT, Silverberg M, Banta-Green C, Weisner C. Defacto long-term opioid therapy for non-cancer pain. Clin J Pain, in press.