Stephen Sidney, MD, MPH

Stephen Sidney, MD, MPH, Associate Director for Clinical Research of the Division of Research (DOR) Kaiser Permanente Northern California, since 1998, is Board certified in internal medicine and certified as a Preventive and Rehabilitative Exercise Program Director by the American College of Sports Medicine. He provides community service as a member of the Alameda County Public Health Advisory Board, as a board member of the Berkeley Society for the Preservation of Traditional Music (Freight and Salvage Coffeehouse) of a support group for parents of students with special education needs in his local school district, and as assistant coach of his son’s high school cross-country team.

Dr. Sidney has authored or co-authored more than 160 peer-reviewed scientific publications while a researcher at the DOR. His research publications cover a diverse range of topics, primarily in the area of cardiovascular epidemiology.

Current Position:

Associate Director for Clinical Research, Division of Research, Kaiser Permanente Northern California

Current research interests:

	Cardiovascular disease
	Physical activity and fitness
	Obesity
	Acute coronary syndrome
	Cerebrovascular disease
	Projects:
	Longitudinal Study of Coronary Heart Disease Risk Factors in Young Adults (CARDIA)
	20-year Changes in Fitness and Cardiovascular Disease Risk (CARDIA Fitness Study)
	Optimal Brain Health in the Elderly
	Fat Redistribution and Metabolic Change in HIV Infection (FRAM)
	Acute Coronary Syndrome: One-year Total Costs and Clinical Outcomes in the Kaiser Permanente Medical Care Program, Northern California Region
	Bariatric Surgery Registry Development
	Secondary Prevention after Ischemic Stroke: A Trial of an Evidence-Based System-Wide Intervention
	Predictors of Spontaneous Cerebral AVM Hemorrhage

Completed Research Projects (partial listing):

	Vasectomy and prostate cancer
	Visceral Fat, Metabolic Rate and CHD Risk in Young Adults
	Epidemiology of benign prostatic hypertrophy
	Health outcomes associated with marijuana use
	Low-dose oral contraceptives and myocardial infarction and stroke
	HRT, Biochemical/Gene Markers and Venous Thromboembolism
	Hormone replacement therapy and myocardial infarction and stroke

Selected Publications:

	Sidney S, Farquhar JW. Cholesterol, cancer, and public health policy. Am J Med 1983;75:494-508.
	Sidney S, Friedman GD, Siegelaub AB. Thinness and mortality. Am J Public Health 1987;77:317-22.
	Sidney S. Vasectomy and the risk of prostatic cancer and benign prostatic hypertrophy. J Urol 1987;138:795-7.
	Sidney S, Caan BJ, Friedman GD. Dietary intake of beta-carotene in non-smokers with and without passive smoking at home. Am J Epidemiol 1989;129:1305-9.
	Sidney S, Tekawa I, Friedman GD. Mentholated cigarette use among multiphasic examinees, 1979 to 1986. Am J Public Health 1989;79:1415-6.
	Sidney S. Evidence of discrepant data regarding trends in marijuana use and supply, 1985-1988. J Psychoactive Drugs 1990;22:319-24.
	Sidney S, Jacobs DR Jr, Haskell WL, Armstrong MA, Dimicco A, Oberman A, Savage PJ, Slattery ML, Sternfeld B, Van Horn L. Comparison of two methods of assessing physical activity in the CARDIA study. Am J Epidemiol 1991;133:1231-45.
	Sidney S, Quesenberry CP Jr, Sadler MC, Guess HA, Lydick EG, Cattolica EV. Vasectomy and the risk of prostate cancer in a cohort of multiphasic health checkup examinees: second report. Cancer Causes and Control 1991;2:113-6.
	Sidney S, Quesenberry CP, Sadler MC, Guess HA, Lydick EG, Cattolica EV. Incidence of surgically treated benign prostatic hypertrophy and of prostate cancer among black and white multiphasic examinees in a prepaid health care plan. Am J Epidemiol 1991;134:825-9.
	Sidney S, Quesenberry CP, Sadler MC, Lydick EG, Guess HA, Cattolica EV. Risk factors for surgically treated benign prostatic hyperplasia in a prepaid health care plan. Urology 1991;38(Supplement):13-9.
	Sidney S, Quesenberry CP Jr, Sadler MC, Cattolica EV, Lydick EG, Guess HA. Reoperation and mortality after surgical treatment of benign prostatic hypertrophy in a large prepaid health care program. Med Care 1992;30:117-25.
	Sidney S, Haskell WL, Crow R, Sternfeld B, Oberman A, Armstrong MA, Cutter GR, Jacobs DR, Savage PJ, Van Horn L. Symptom-limited graded treadmill exercise testing in young adults in the CARDIA study. Med Sci Sports Exerc 1992;24:177-83.
	Sidney S, Tekawa IS, Friedman GD. A prospective study of cigarette tar yield and lung cancer. Cancer Causes Control 1993;4:3-9.
	Sidney S, Sternfeld B, Gidding SS, Jacobs DR Jr., Bild DE, Oberman A, Haskell WL, Crow RS, Gardin JM. Cigarette smoking and submaximal exercise test duration in a biracial population of young adults: the CARDIA study. Med Sci Sports Exerc 1993;25:911-6.
	Sidney S, Tekawa IS, Friedman GD, Sadler MC, Tashkin DP. Mentholated cigarette use and lung cancer. Arch Intern Med 1995;155:727-32.
	Sidney S, Sternfeld B, Haskell WL, Jacobs DR Jr, Chesney MA, Hulley SB. Television viewing and cardiovascular risk factors in young adults: the CARDIA study. Ann Epidemiol 1996;6:154-9.
	Sidney S, Beck JE, Tekawa IS, Quesenberry CP Jr, Friedman GD. Marijuana use and mortality. Am J Public Health 1997;87:585-90.
	Sidney S, Petitti DB, Quesenberry CP Jr. Myocardial infarction and the use of estrogen and estrogen/progestogen therapy in postmenopausal women. Ann Intern Med 1997;127:501-8.
	Sidney S, Quesenberry CP Jr, Friedman GD, Tekawa IS. Marijuana use and cancer incidence (California, United States). Cancer Causes Control 1997;8:722-8.
	Sidney S, Sternfeld B, Haskell WL, Quesenberry CP Jr, Crow RS, Thomas RJ. Seven-year change in graded exercise treadmill test performance in young adults in the CARDIA study. Med Sci Sports Exerc 1998;30:427-33.
	Sidney S, Siscovick DS, Petitti DB, Schwartz SM, Quesenberry CP Jr, Psaty BM, Raghunathan TE, Kelaghan J, Koepsell TD. Myocardial infarction and use of low-dose oral contraceptives: a pooled analysis of two U.S. studies. Circulation 1998;98:1058-63.
	Sidney S, Lewis CE, Hill JO, Quesenberry CP Jr, Stamm ER, Scherzinger A, Tolan K, Ettinger B. Association of total and central adiposity measures with fasting insulin in a biracial population of young adults with normal glucose tolerance: the CARDIA study. Obes Res1999;7:265-72.
	Sidney S. Marijuana use in HIV-positive and AIDS patients: results of an anonymous mail survey. J Cannabis Therapeutics 2001;1(3/4):35-41.
	Wheeler K, Lewis CW, Williams OD, Sidney S, Kiefe CI, Hulley SB. Oral contraceptives and cardiovascular disease risk in African-American and white women: the CARDIA Study. ClinJ Women’s Health 2001;1:175-83.
	Klatsky A, Armstrong MA, Friedman GD, Sidney S. Alcohol drinking and risk of hemorrhagic stroke. Am J Cardiol 2001; 88:703-6.
	Keegan TH, Kelsey JL, Sidney S, Quesenberry CP Jr. Foot problems as risk factors for fractures. Am J Epidemiol 2002;155(10):926-31.
	Kim C, Siscovick DS, Sidney S, Lewis CE, Kiefe CI, Koepsell TD. Oral contraceptive use and association with glucose, insulin, and diabetes in young women: The CARDIA Study. Diabetes Care 2002;25:1027-32.
	Klatsky AL, Armstrong MA, Friedman GD, Sidney S. Alcohol drinking and risk of hemorrhagic stroke. Neuroepidemiology 2002;21(3):115-22.
	Klein D, Hurley LB, Quesenberry Jr CP, Sidney S. Do protease inhibitors increase the risk for coronary heart disease in patients with HIV-1 infection? J Acquir Immune Defic Syndr 2002;30(5):471-7.
	Sharp Ta, Bell ML, Grunwald GK, Schmitz KH, Sidney S, Lewis CE, Tolan K, Hill JO. Differences in resting metabolic rate between White and African-American young adults. Obes Res 2002;10(8):726-32.
	Gerberich SG, Sidney S, Braun BL, Tekawa IS, Tolan KK, Quesenberry CP. Marijuana use and injury events resulting in hospitalization. Ann Epidemiol 2003 Apr;13(4):230-7
	Keegan TH, Gopalakrishnan G, Sidney S, Quesenberry CP Jr, Kelsey JL. Hormone replacement therapy and risk for foot, distal forearm, proximal humerus,and pelvis fractures. Osteoporos Int 2003;14:469-75.
	Carnethon MR, Jacobs DR Jr, Sidney S, Liu K. Influence of Autonomic Nervous System Dysfunction on the Development of Type 2 Diabetes: The CARDIA study. Diabetes Care. 2003 Nov;26(11):3035-3041.
	Carnethon MR, Gidding SS, Nehgme R, Sidney S, Jacobs DR Jr, Liu K. Cardiorespiratory fitness in young adulthood and the development of cardiovascular disease risk factors. JAMA 2003;290:3092-100.
	Keegan TH, Kelsey JL, King AC, Quesenberry CP Jr, Sidney S. Characteristics of fallers who fracture at the foot, distal forearm, proximal humerus, pelvis, and shaft of the tibia/fibula compared with fallers who do not fracture. Am J Epidemiol 2004;159:192-203.
	Sidney S, Petitti DB, Soff GA, Cundiff DL, Tolan KK, Quesenberry CP Jr. Venous thromboembolic disease in users of low-estrogen combined estrogen-progestin oral contraceptives. Contraception. 2004 Jul;70(1):3-10.
	Chu SP, Kelsey JL, Keegan TH, Sternfeld B, Prill M, Quesenberry CP, Sidney S. Risk factors for proximal humerus fracture. Am J Epidemiol. 2004 Aug 15;160(4):360-7.
	Cushman M, Kuller LH, Prentice R, Rodabough RJ, Psaty BM, Stafford RS, Sidney S, Rosendaal FR; Women's Health Initiative Investigators. Estrogen plus progestin and risk of venous thrombosis. JAMA. 2004 Oct 6;292(13):1573-80.
	Iribarren C, Gross MD, Darbinian JA, Jacobs Jr DR, Sidney S, Loria C. Association of Lipoprotein-Associated Phospholipase A2 Mass and Activity With Calcified Coronary Plaque in Young Adults. The CARDIA Study. Arterioscler Thromb Vasc Biol. 2004 Oct 21 [Epub ahead of print]
	Kelsey JL, Prill MM, Keegan TH, Tanner HE, Bernstein AL, Quesenberry CP Jr, Sidney S. Reducing the risk for distal forearm fracture: preserve bone mass, slow down,and don't fall.Osteoporos Int. 2004 Oct 26 [Epub ahead of print]
	Gomez SL, Kelsey JL, Glaser SL, Lee MM, Sidney S. Immigration and acculturation in relation to health and health-related risk factors among specific asian subgroups in a health maintenance organization. Am J Public Health. 2004 Nov;94(11):1977-84.
	Carnethon MR, Loria CM, Hill JO, Sidney S, Savage PJ, Liu K. Risk Factors for the Metabolic Syndrome: The Coronary Artery Risk Development in Young Adults (CARDIA) study, 1985-2001. Diabetes Care. 2004 Nov;27(11):2707-15.
	Mustillo S, Krieger N, Gunderson EP, Sidney S, McCreath H, Kiefe CI. Self-Reported Experiences of Racial Discrimination and Black-White Differences in Preterm and Low-Birthweight Deliveries: The CARDIA Study. Am J Public Health. 2004 Dec; 94(12):2125-31.
	Gomez SL, Kelsey JL, Glaser SL, Lee MM, Sidney S. Inconsistencies between self-reported ethnicity and ethnicity recorded in a health maintenance organization. Ann Epidemiol. 2005 Jan;15(1):71-79.
	Kelsey JL, Keegan TH, Prill MM, Quesenberry CP Jr, Sidney S. Risk factors for fracture of the shafts of the tibia and fibula in older individuals. Osteoporos Int. 2005 Aug 9; [Epub ahead of print]
	Whitmer RA, Sidney S, Selby J, Johnston SC, Yaffe K. Midlife cardiovascular risk factors and risk of dementia in late life. Neurology. 2005 Jan 25;64(2):277-81.
	Kelsey JL, Prill MM, Keegan TH, Quesenberry CP Jr, Sidney S. Risk Factors for Pelvis Fracture in Older Persons. Am J Epidemiol. 2005 Oct 12; [Epub ahead of print]
	Gunderson EP, Whitmer RA, Lewis CE, Quesenberry CP, West DS, Sidney S. Do Long-Term HDL-C Declines Associated with a First Birth Vary by apo E Phenotype? The Coronary Artery Risk Development in Young Adults (CARDIA) Study. J Womens Health (Larchmt). 2005 Dec;14(10):917-28.
	Fullerton HJ, Achrol AS, Johnston SC, McCulloch CE, Higashida RT, Lawton MT, Sidney S, Young WL. Long-Term Hemorrhage Risk in Children Versus Adults With Brain Arteriovenous Malformations. Stroke. 2005 Sep 1; [Epub ahead of print]
	Sidney S, Sorel M, Quesenberry CP Jr, Deluise C, Lanes S, Eisner MD. COPD and Incident Cardiovascular Disease Hospitalizations and Mortality: Kaiser Permanente Medical Care Program. Chest. 2005 Oct;128(4):2068-75.
	Habel LA, Pressman A, Ettinger B, Sidney S, Suh-Burgmann B, Fehrenbacher L, Quesenberry CP. Use of raloxifene among women with a history of breast cancer. Breast Cancer Res Treat 2005 [Epub ahead of print].
	Sidney S, Sorel M, Quesenberry CP Jr, Deluise C, Lanes S, Eisner MD. COPD and incident cardiovascular disease hospitalizations and mortality: Kaiser Permanente Medical Care Program. Chest 2005;128:2068-75.
	Pletcher MJ, Kiefe CI, Sidney S, Carr JJ, Lewis CE, Hulley SB. Cocaine and coronary calcification in young adults The Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am Heart J 2005;150:921-6.
	Kelsey JL, Prill MM, Keegan TH, Quesenberry CP Jr, Sidney S. Risk factors for pelvis fracture in older persons. Am J Epidemiol 2005;162:879-86.
	Achrol AS, Pawlikowska L, McCulloch CE, Poon KY, Ha C, Zaroff JG, Johnston SC, Lee C, Lawton MT, Sidney S, Marchuk DA, Kwok PY, Young WL; UCSF BAVM Study Project. Tumor necrosis factor-alpha-238G>A promoter polymorphism is associated with increased risk of new hemorrhage in the natural course of patients with brain arteriovenous malformations. Stroke 2006;237:231-4.
	Thom T, Haase N, Rosamond W, Howard VJ, Rumsfeld J, Manolio T, Zheng ZJ, Flegal K, O'donnell C, Kittner S, Lloyd-Jones D, Goff DC Jr, Hong Y, Adams R, Friday G, Furie K, Gorelick P, Kissela B, Marler J, Meigs J, Roger V, Sidney S, Sorlie P,Steinberger J, Wasserthiel-Smoller S, Wilson M, Wolf P. Heart Disease and Stroke Statistics--2006 Update. A Report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2006 Jan 11; [Epub ahead of print].
	Cohen S, Schwartz JE, Epel E, Kirschbaum C, Sidney S, Seeman T. Socioeconomic Status, Race, and Diurnal Cortisol Decline in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Psychosom Med. 2006 Jan-Feb;68(1):41-50.
	Tien PC, Benson C, Zolopa AR, Sidney S, Osmond D, Grunfeld C. The Study of Fat Redistribution and Metabolic Change in HIV Infection (FRAM): Methods, Design, and Sample Characteristics. Am J Epidemiol. 2006 Mar 8; [Epub ahead of print]
	Curb JD, Prentice RL, Bray PF, Langer RD, Van Horn L, Barnabei VM, Bloch MJ, Cyr MG, Gass M, Lepine L, Rodabough RJ, Sidney S, Uwaifo GI, Rosendaal FR. Venous thrombosis and conjugated equine estrogen in women without a uterus. Arch Intern Med. 2006 Apr 10;166(7):772-80.
	Pawlikowska L, Poon KY, Achrol AS, McCulloch CE, Ha C, Lum K, Zaroff JG, Ko NU, Johnston SC, Sidney S, Marchuk DA, Lawton MT, Kwok PY, Young WL. Apolipoprotein E epsilon2 is associated with new hemorrhage risk in brain arteriovenous malformations. Neurosurgery 2006;58:838-43; discussion 838-43.
	Yan LL, Liu K, Daviglus ML, Colangelo LA, Kiefe CI, Sidney S, Matthews KA, Greenland P. Education, 15-year risk factor progression, and coronary artery calcium in young adulthood and early middle age: the Coronary Artery Risk Development in Young Adults study. JAMA 2006;295:1793-800.
	Lauderdale DS, Knutson KL, Yan LL, Rathouz PJ, Hulley SB, Sidney S, Liu K. Objectively measured sleep characteristics among early-middle-aged adults. Am J Epidemiol 2006; [Epub ahead of print].
	Li W, Keegan TH, Sternfeld B, Sidney S, Quesenberry Jr CP, Kelsey JL. Outdoor falls among middle-aged and older adults: a neglected public health problem. Am J Public Health 2006; [Epub ahead of print].
	Tien PC, Benson C, Zolopa AR, Sidney S, Osmond D, Grunfeld C. The study of fat redistribution and metabolic change in HIV infection (FRAM): methods, design, and sample characteristics. Am J Epidemiol 2006;163:860-9.
	Kizilbash MA, Carnethon MR, Chan C, Jacobs DR, Sidney S, Liu K. The temporal relationship between heart rate recovery immediately after exercise and the metabolic syndrome: the CARDIA Study. Eur Heart J 2006; May 25; [Epub ahead of print].
	Yan LL, Liu K, Daviglus ML, Colangelo LA, Kiefe CI, Sidney S, Matthews KA, Greenland P. Education, 15-year risk factor progression, and coronary artery calcium in young adulthood and early middle age: the Coronary Artery Risk Development in Young Adults study. JAMA 2006;295:1793-800.
	Pawlikowska L, Poon KY, Achrol AS, McCulloch CE, Ha C, Lum K, Zaroff JG, Ko NU, Johnston SC, Sidney S, Marchuk DA, Lawton MT, Kwok PY, Young WL. Apolipoprotein E epsilon2 is associated with new hemorrhage risk in brain arteriovenous malformations. Neurosurgery 2006;58:838-43; discussion 838-43.
	Pletcher MJ, Kertesz SG, Sidney S, Kiefe CI, Hulley SB. Incidence and antecedents of nonmedical prescription opioid use in four US communities: the Coronary Artery Risk Development in Young Adults (CARDIA) prospective cohort study. Drug Alcohol Depend 2006; [Epub ahead of print].
	Curb JD, Prentice RL, Bray PF, Langer RD, Van Horn L, Barnabei VM, Bloch MJ, Cyr MG, Gass M, Lepine L, Rodabough RJ, Sidney S, Uwaifo GI, Rosendaal FR. Venous thrombosis and conjugated equine estrogen in women without a uterus. Arch Intern Med 2006;166:772-80.