Gender, Obesity, C-Reactive Protein and Oxidative Stress
Epidemiological data and a trial in smokers suggest that Vitamin C supplementation may decrease C-reactive protein, a marker of inflammation associated with heart disease. The current study is a randomized trial of vitamin C versus placebo among obese patients with elevated levels of C-reactive protein.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Corley, Douglas
Smoking Cessation and Relapse: California-based Samoans
This study seeks to understand better the processes and experiences that lead to smoking initiation, maintenance, cessation, and relapse among California-based Samoans.
Funder: Tobacco-Related Disease Research Program
Principal Investigator: Gruskin, Elisabeth
Measuring Prenatal Tobacco Exposure in Newborn Blood Spots
This study will utilize stored biological specimens obtained at midpregnancy maternal screening (serum), from fetal cord blood collected at delivery, and blood spots collected during newborn genetic disease screening. The study will determine how levels of hemoglobin adducts measured in newborn blood spots reflect prenatal tobacco exposure in comparison to cotinine levels measured in midpregnancy maternal serum and in fetal cord blood.
Funder: Tobacco-Related Disease Research Program
Principal Investigator: DeLorenze, Gerald
The Impact of Secondhand Smoke Exposure on COPD Outcomes
This study evaluates the role of education in the incidence of diabetic complications in a large, well-characterized population within an integrated, managed care setting (Kaiser Permanente).
Funder: Tobacco-Related Disease Research Program
Principal Investigator: Iribarren, Carlos
UCSF Center of Excellence on Secondhand Smoke (aka FLOW-FAMRI)
This study seeks to elucidate the factors that determine the risk of developing disability and poor health outcomes among adults with COPD, controlling for degree of pulmonary function impairment; evaluate the impact of specific functional limitations on the risk of developing disability in daily activities and work among relatively young adults with COPD; and elucidate the impact of disability on future adverse health outcomes.
Funder: Flight Attendants' Medical Research Institute
Principal Investigator: Iribarren, Carlos
Stopping smoking during first year of substance use treatment predicted 9-year alcohol and drug treatment outcomes
Tsoh, J. Y.;
Chi, F. W.;
Mertens, J. R.;
Weisner, C. M.;
Drug Alcohol Depend
Nov 1 2010
PubMed abstract
»
Heavy Smoking in Midlife and Long-term Risk of Alzheimer Disease
and Vascular Dementia
Rusanen, M.;
Kivipelto, M.;
Quesenberry, C. P., Jr.;
Zhou, J.;
Whitmer, R. A.;
Arch Intern Med
Oct 25 2010
PubMed abstract
»
Cigarette Smoking and Adenocarcinomas of the Esophagus and
Esophagogastric Junction: A Pooled Analysis From the International
BEACON Consortium
Cook, M. B.;
Kamangar, F.;
Whiteman, D. C.;
Freedman, N. D.;
Gammon, M. D.;
Bernstein, L.;
Brown, L. M.;
Risch, H. A.;
Ye, W.;
Sharp, L.;
Pandeya, N.;
Webb, P. M.;
Wu, A. H.;
Ward, M. H.;
Giffen, C.;
Casson, A. G.;
Abnet, C. C.;
Murray, L. J.;
Corley, D. A.;
Nyren, O.;
Vaughan, T. L.;
Chow, W. H.;
J Natl Cancer Inst
Aug 17 2010
PubMed abstract
»
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Furberg, H.;
Kim, Y.;
Dackor, J.;
Boerwinkle, E.;
Franceschini, N.;
Ardissino, D.;
Bernardinelli, L.;
Mannucci, P.L.;
Mauri, F.;
Merlini, P.A.;
Absher, D.;
Assimes, T.L.;
Fortmann, S.P.;
Iribarren, C.;
et al ...;
Tobacco and Genetics Consortium;
Nat Genet
42
(5):
441-7
May 2010
PubMed abstract
»
Passive Smoke Exposure and Circulating Carotenoids in the CARDIA
Study
Widome, R.;
Jacobs, D. R., Jr.;
Hozawa, A.;
Sijtsma, F.;
Gross, M.;
Schreiner, P. J.;
Iribarren, C.;
Ann Nutr Metab
56
(2):
113-118
Jan 29 2010
PubMed abstract
»
Smoking and maternal and neonatal genetic polymorphisms
Delorenze, G.;
600-605
2010
PubMed abstract
»
Assessing tumor mutations to gain insight into base excision repair
sequence polymorphisms and smoking in colon cancer
Curtin, K.;
Samowitz, W. S.;
Wolff, R. K.;
Ulrich, C. M.;
Caan, B. J.;
Potter, J. D.;
Slattery, M. L.;
Cancer Epidemiol Biomarkers Prev
18
(12):
3384-8
Dec 2009
PubMed abstract
»
Medical history, body size, and cigarette smoking in relation to fatal prostate cancer
Weinmann, S.;
Shapiro, J. A.;
Rybicki, B. A.;
Enger, S. M.;
Van Den Eeden, S. K.;
Richert-Boe, K. E.;
Weiss, N. S.;
Cancer Causes Control
21
(1):
117-25
Jan 2010
PubMed abstract
»
The impact of SHS exposure on health status and exacerbations among
patients with COPD
Eisner, M. D.;
Iribarren, C.;
Yelin, E. H.;
Sidney, S.;
Katz, P. P.;
Sanchez, G.;
Blanc, P. D.;
Int J Chron Obstruct Pulmon Dis
4
(1):
169-76
2009
PubMed abstract
»
Smoking enhances risk for new external genital warts in men
Wiley, D. J.;
Elashoff, D.;
Masongsong, E. V.;
Harper, D. M.;
Gylys, K. H.;
Silverberg, M. J.;
Cook, R. L.;
Johnson-Hill, L. M.;
Int J Environ Res Public Health
6
(3):
1215-34
Mar 2009
PubMed abstract
»
Somatic alterations, metabolizing genes and smoking in rectal
cancer
Curtin, K.;
Samowitz, W. S.;
Wolff, R. K.;
Herrick, J.;
Caan, B. J.;
Slattery, M. L.;
Int J Cancer
125
(1):
158-64
Jul 1 2009
PubMed abstract
»
Self-initiated tobacco cessation and substance use outcomes among
adolescents entering substance use treatment in a managed care
organization
Campbell, C. I.;
Chi, F.;
Sterling, S.;
Kohn, C.;
Weisner, C.;
Addict Behav
34
(2):
171-9
Feb 2009
PubMed abstract
»
Cigarette smoking and the risk of Barrett's esophagus
Kubo, A.;
Levin, T. R.;
Block, G.;
Rumore, G.;
Quesenberry, C. P., Jr.;
Buffler, P.;
Corley, D. A.;
Cancer Causes Control
20
(3):
303-11
Apr 2009
PubMed abstract
»
Prevalence and correlates of substance use among South African
primary care clinic patients
Ward, C. L.;
Mertens, J. R.;
Flisher, A. J.;
Bresick, G. F.;
Sterling, S. A.;
Little, F.;
Weisner, C. M.;
Subst Use Misuse
43
(10):
1395-410
2008
PubMed abstract
»
Occupational exposures and the risk of COPD: dusty trades revisited
Blanc, P. D.;
Iribarren, C.;
Trupin, L.;
Earnest, G.;
Katz, P. P.;
Balmes, J.;
Sidney, S.;
Eisner, M. D.;
Thorax
64
(1):
6-12
Jan 2009
PubMed abstract
»