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Research

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Sleep Disorders

The most common sleep disorders are insomnia, sleep apnea, restless legs syndrome and narcolepsy, according to the National Institutes of Health. Our researchers study causes and treatment as well as opportunities for prevention. 

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The Overlap Syndrome of COPD and OSA: Determinants of Health Status and Outcomes

The FLOW Study also seeks to examine factors contributing to the development of disability among COPD patients. The FLOW Study is currently measuring respiratory impairment factors while subjects are awake, utilizing such measures as spirometry and oxygen saturation.
Funder: National Heart, Lung, and Blood Institute
Principal Investigator: Iribarren, Carlos

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Common variants in P2RY11 are associated with narcolepsy

Kornum, B. R.; Kawashima, M.; Faraco, J.; Lin, L.; Rico, T. J.; Hesselson, S.; Axtell, R. C.; Kuipers, H.; Weiner, K.; Hamacher, A.; Kassack, M. U.; Han, F.; Knudsen, S.; Li, J.; Dong, X.; Winkelmann, J.; Plazzi, G.; Nevsimalova, S.; Hong, S. C.; Honda, Y.; Honda, M.; Hogl, B.; Ton, T. G.; Montplaisir, J.; Bourgin, P.; Kemlink, D.; Huang, Y. S.; Warby, S.; Einen, M.; Eshragh, J. L.; Miyagawa, T.; Desautels, A.; Ruppert, E.; Hesla, P. E.; Poli, F.; Pizza, F.; Frauscher, B.; Jeong, J. H.; Lee, S. P.; Strohl, K. P.; Longstreth, W. T., Jr.; Kvale, M.; Dobrovolna, M.; Ohayon, M. M.; Nepom, G. T.; Wichmann, H. E.; Rouleau, G. A.; Gieger, C.; Levinson, D. F.; Gejman, P. V.; Meitinger, T.; Peppard, P.; Young, T.; Jennum, P.; Steinman, L.; Tokunaga, K.; Kwok, P. Y.; Risch, N.; Hallmayer, J.; Mignot, E.;
Nat Genet  
Dec 19 2010
PubMed abstract  »

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Reliability and validity of two self-administered questionnaires for screening restless legs syndrome in population-based studies

Popat, R. A.; Van Den Eeden, S. K.; Tanner, C. M.; Kushida, C. A.; Rama, A. N.; Black, J. E.; Bernstein, A.; Kasten, M.; Chade, A.; Leimpeter, A.; Cassidy, J.; McGuire, V.; Nelson, L. M.;
Sleep Med  11 (2): 154-60
Feb 2010
PubMed abstract  »

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Short sleep duration and incident coronary artery calcification

King, C. R.; Knutson, K. L.; Rathouz, P. J.; Sidney, S.; Liu, K.; Lauderdale, D. S.;
JAMA   300 (24): 2859-66
Dec 24 2008
PubMed abstract  »

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Sleep problems in children with autism spectrum disorders, developmental delays, and typical development: a population-based study

Krakowiak, P.; Goodlin-Jones, B.; Hertz-Picciotto, I.; Croen, L. A.; Hansen, R. L.;
J Sleep Res   17 (2): 197-206
Jun 2008
PubMed abstract  »

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Short sleep duration in infancy and risk of childhood overweight

Taveras, E. M.; Rifas-Shiman, S. L.; Oken, E.; Gunderson, E. P.; Gillman, M. W.;
Arch Pediatr Adolesc Med   162 (4): 305-11
Apr 2008
PubMed abstract  »

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Association of fewer hours of sleep at 6 months postpartum with substantial weight retention at 1 year postpartum

Gunderson, E. P.; Rifas-Shiman, S. L.; Oken, E.; Rich-Edwards, J. W.; Kleinman, K. P.; Taveras, E. M.; Gillman, M. W.;
Am J Epidemiol   167 (2): 178-87
Jan 15 2008
PubMed abstract  »

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Objectively measured sleep characteristics among early-middle-aged adults: the CARDIA study

Lauderdale, D. S.; Knutson, K. L.; Yan, L. L.; Rathouz, P. J.; Hulley, S. B.; Sidney, S.; Liu, K.;
Am J Epidemiol   164 (1): 5-16
Jul 1 2006
PubMed abstract  »

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Use of a dummy (pacifier) during sleep and risk of sudden infant death syndrome (SIDS): population based case-control study

Li, D. K.; Willinger, M.; Petitti, D. B.; Odouli, R.; Liu, L.; Hoffman, H. J.;
BMJ   332 (7532): 18-22
Jan 7 2006
PubMed abstract  »

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Use of a dummy (pacifier) during sleep and risk of sudden infant death syndrome (SIDS): population based case-control study

Li, D. K.; Willinger, M.; Petitti, D. B.; Odouli, R.; Liu, L.; Hoffman, H. J.;
BMJ   332 (7532): 18-22
Jan 7 2006
PubMed abstract  »

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Infant sleeping position and the risk of sudden infant death syndrome in California, 1997-2000

Li, D. K.; Petitti, D. B.; Willinger, M.; McMahon, R.; Odouli, R.; Vu, H.; Hoffman, H. J.;
Am J Epidemiol   157 (5): 446-55
Mar 1 2003
PubMed abstract  »

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Maternal pre-eclampsia/eclampsia and the risk of sudden infant death syndrome in offspring

Li, D. K.; Wi, S.;
Paediatr Perinat Epidemiol   14 (2): 141-4
Apr 2000
PubMed abstract  »

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Maternal placental abnormality and the risk of sudden infant death syndrome

Li, D. K.; Wi, S.;
Am J Epidemiol   149 (7): 608-11
Apr 1 1999
PubMed abstract  »