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Research

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Obesity

Sixty-six percent of Americans are overweight or obese, according to the Centers for Disease Control and Prevention. Through such studies as Alive!, our researchers study obesity through many lenses, including diet and physical activity, metabolic syndrome, and the role of obesity in diabetes, heart disease, and dementia.

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Obesity in Ovarian Cancer Prognosis

The research project aims to examine the association of weight and weight change on ovarian cancer survival and CA-125 levels, a tumor marker used routinely in the clinical management of ovarian cancer.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence

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Kaiser South San Francisco Bariatric Surgery Retrospective Review 2006-2008

Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Li, Robert

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Neighborhoods and Obesity in Preadolescent Girls: Part II

This project investigates how city planning policies and the neighborhood environment affect physical activity and diet behaviors of seven-year-old girls already participating in a longitudinal observational study about the predictors of pubertal transition. 
Funder: California Breast Cancer Research Program
Principal Investigator: Kushi, Lawrence

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Obesity, Adipocytokines and Cognitive Aging

This project examines the associations between overall obesity, visceral obesity, leptin, adiponectin and levels of cognitive functioning, as well as cognitive decline in a cohort of elderly community-dwelling Latinos.
Funder: National Institute on Aging
Principal Investigator: Whitmer, Rachel

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Perceptions of Middle School Educators in Hawai'i about School-based Gardening and Child Health

Ahmed, A. T.; Oshiro, C. E.; Loharuka, S.; Novotny, R.;
Hawaii medical journal   70 (7 Suppl 1): 11-5
Jul 2011
PubMed abstract  »

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Fat mass modifies the association of fat-free mass with symptom-limited treadmill duration in the Coronary Artery Risk Development in Young Adults (CARDIA) Study

Zhu, N.; Jacobs, D. R., Jr.; Sidney, S.; Sternfeld, B.; Carnethon, M.; Lewis, C. E.; Shay, C. M.; Sood, A.; Bouchard, C.;
Am J Clin Nutr 
Jun 8 2011
PubMed abstract  »

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Lower Extremity Fat Mass Is Associated With Insulin Resistance in Overweight and Obese Individuals: The CARDIA Study

Shay, C. M.; Carnethon, M. R.; Church, T. R.; Hankinson, A. L.; Chan, C.; Jacobs Jr, D. R.; Lewis, C. E.; Schreiner, P. J.; Sternfeld, B.; Sidney, S.;
Obesity (Silver Spring) 
May 26 2011
PubMed abstract  »

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Surgical treatment of morbid obesity among patients with bipolar disorder: a research agenda

Ahmed, A. T.; Blair, T. R.; McIntyre, R. S.;
Adv Ther  
Apr 4 2011
PubMed abstract  »

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Lack of Association Between Insulin Sensitivity and Colorectal Adenoma Risk

Sedjo, R. L.; D'Agostino, R. B., Jr.; Ahnen, D.; Levin, T. R.; Haffner, S. M.; Tooze, J. A.; Byers, T.;
Nutr Cancer   1-6
Dec 13 2010
PubMed abstract  »

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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

Speliotes, E. K.; Willer, C. J.; Berndt, S. I.; ...; Iribarren, C.; ...; Hirschhorn, J. N.; Ingelsson, E.; Loos, R. J.;
Nat Genet   epub
Oct 10 2010
PubMed abstract  »

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Prevalence and predictors of hepatic steatosis in adults with newly diagnosed chronic liver disease due to hepatitis C

Hayman, A. V.; Sofair, A. N.; Manos, M. M.; Thomas, A.; Terrault, N.; Ness, G. V.; Stabach, N.; Robert, M.; Rumore, G.; Corless, C.; Bell, B.; Bialek, S.; Zaman, A.;
Medicine (Baltimore)   88 (5): 302-6
Sep 2009
PubMed abstract  »

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Development of Alive! (A Lifestyle Intervention Via Email), and its effect on health-related quality of life, presenteeism, and other behavioral outcomes: randomized controlled trial

Block, G.; Sternfeld, B.; Block, C. H.; Block, T. J.; Norris, J.; Hopkins, D.; Quesenberry, C. P., Jr.; Husson, G.; Clancy, H. A.;
J Med Internet Res   10 (4): e43
 2008
PubMed abstract  »

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Presence of depressive symptoms during early pregnancy and the risk of preterm delivery: a prospective cohort study

Li, D.; Liu, L.; Odouli, R.;
Hum Reprod   24 (1): 146-53
Jan 2009
PubMed abstract  »

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Pre-diagnosis body mass index, post-diagnosis weight change, and prognosis among women with early stage breast cancer

Caan, B. J.; Kwan, M. L.; Hartzell, G.; Castillo, A.; Slattery, M. L.; Sternfeld, B.; Weltzien, E.;
Cancer Causes Control   19 (10): 1319-28
Dec 2008
PubMed abstract  »

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Short sleep duration in infancy and risk of childhood overweight

Taveras, E. M.; Rifas-Shiman, S. L.; Oken, E.; Gunderson, E. P.; Gillman, M. W.;
Arch Pediatr Adolesc Med   162 (4): 305-11
Apr 2008
PubMed abstract  »

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Central obesity and increased risk of dementia more than three decades later

Whitmer, R. A.; Gustafson, D. R.; Barrett-Connor, E.; Haan, M. N.; Gunderson, E. P.; Yaffe, K.;
Neurology   71 (14): 1057-64
Sep 30 2008
PubMed abstract  »

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Abdominal obesity and the risk of esophageal and gastric cardia carcinomas

Corley, D. A.; Kubo, A.; Zhao, W.;
Cancer Epidemiol Biomarkers Prev   17 (2): 352-8
Feb 2008
PubMed abstract  »

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BMI and health status among adults with asthma

Vortmann, M.; Eisner, M. D.;
Obesity (Silver Spring)   16 (1): 146-52
Jan 2008
PubMed abstract  »

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Body mass index and weight gain prior to pregnancy and risk of gestational diabetes mellitus

Hedderson, M. M.; Williams, M. A.; Holt, V. L.; Weiss, N. S.; Ferrara, A.;
Am J Obstet Gynecol   198 (4): 409 e1-7
Apr 2008
PubMed abstract  »