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Research

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Health Services Research

From accessibility to quality, patient experience to cost, our researchers examine the delivery of health care and how to make it better, more efficient, more effective.

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Use of secure electronic messaging with providers in KPNC

We will examine patient use of secure electronic messaging services (e.g., "Email my doctor"), and survey responses about experience with and perceptions of secure electronic messaging.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Reed, Mary

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Learnings in Diabetes Prevention from an Integrated Delivery System

Includes evaluation studies of a health plan employer partnership that identifies employees at high risk for diabetes on intervenes using outreach and communication, feedback, incentives, and health coaching to change behaviors and reduce risk; a broader evaluation of a new telephone health coaching program that will ultimately be available to all adult members; and the Regional Perinatal Service Centers region-wide program for reducing risk among women who have had gestational diabetes mellitus.
Funder: Centers for Disease Control and Prevention
Principal Investigator: Selby, Joe

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Effectiveness of medical therapy, endovascular therapy, and surgery for peripheral arterial disease

The objective is to inform current practice regarding peripheral arterial disease (PAD) treatment as follows:  1) to assemble a registry of PAD patients (n=60,000) in 2 integrated healthcare delivery systems and collect detailed chart abstracted procedural data (n=3,000) for those who undergo endovascular or surgical revascularization; 2) to describe demographics, co-morbidities, medications, and risk factor control of diagnosed PAD patients by medical therapy only, endovascular therapy or surgery; and 3) to assess the comparative effectiveness of surgery versus endovascular therapy for PAD. 
Funder: Agency for Healthcare Research and Quality
Principal Investigator: Go, Alan

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Effect of Intimate Partner Violence on Women's Health Care Utilization

This project will (1) Determine the patterns of current health care utilization (mental health, primary care, specialty care, emergency department, inpatient, pharmacy, laboratory and radiology) and costs among women who are and are not experiencing intimate partner violence (IPV); (2) test the hypothesis that  women currently experiencing IPV have lower rates of receipt of routine preventive care (PAP smear, mammogram, CRC screening) than those not experiencing IPV; and  (3) determine how clinical identification of IPV-affected women affects health care utilization.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Ahmed, Ameena

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Diverse Autism Registry for Effectiveness Studies

The goal of the study is to create a large, comprehensive and dynamic autism spectrum disorder (ASD) registry across several integrated health systems.  The first phase of the study will look at variability across the participating health plans in the prevalence of ASD, in medical and psychiatric co-morbidities in the ASD population, and in the use of psychotropic medications to treat children and adolescents with ASDs.  The second phase will look at different treatment approaches, and treatment burdens for families of children with ASD, and parental perceptions of the efficacy of different treatments.  During the second phase of the study, parents of children diagnosed with an ASD who are Kaiser Permanente members will be invited to complete a Web survey and contribute a blood or saliva sample for future ASD research.
Funder: National Institute of Mental Health
Principal Investigator: Croen, Lisa

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Comparing the long-term and real world effectiveness of initial management strategies for DCIS

Use data from the DCIS study (initially funded via the Cancer Research Network) to generate real world evidence regarding risk of recurrence and treatment for recurrence after initial diagnosis and treatment.  Specifically, we will 1) Determine type of surgery and the rate of complications from surgery including reconstructive surgery after recurrence, 2) Use the variables in the study to create a personalized risk score for use in predicting the rate of recurrence in an individual patient and 3) Study the timing, side effects, compliance of tamoxifen therapy and the relationship between duration of tamoxifen on timing of local recurrence and the use of tamoxifen at diagnosis of DCIS recurrence. 
Funder: Agency for Healthcare Research and Quality
Principal Investigator: Habel, Laurel

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Accelerating Change and Transformation in Organizations and Networks (ACTION II)

Funder: Agency for Healthcare Research and Quality
Principal Investigator: Schmittdiel, Julie

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Increasing Participation in Cancer Clinical Trials: Diversity Supplement

To test an organizational intervention to increase participation in national, cooperative group, cancer clinical trials.
Funder: National Cancer Institute
Principal Investigator: Somkin, Carol

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Developing an HMORN Collaboratory

In collaboration with the National Institutes of Health, the Collaboratory will strengthen the HMORN research ceners' partnerships with their parent health systems, enabling more robust evidence translation capabailities.
Funder: National Cancer Institute
Principal Investigator: Habel, Laurel

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Randomized Screening Trial for Melanoma in a Large Cancer Research Network

The specific aims of this project are to produce a state-of-the-art, web-based educational program for primary care clinicians (PCCs) to screen for skin cancer by full body skin examination (FBSE).
Funder: Melanoma Research Alliance
Principal Investigator: Asgari, Maryam

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UCSF/Kaiser-DOR Program for Developing Independent Women's Health Researchers

Funder: Nat. Inst. of Child Health and Human Dev.
Principal Investigator: Selby, Joe

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Development and Implementation of Novel Molecular Diagnostic Tools to Guide Combination Therapy for Malignant Glioma Patients


Funder: Ivy Foundation
Principal Investigator: Peak, Scott

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Patient Safety Screening Study

Funder: Univ. of Massachusetts
Principal Investigator: McCormick, Mark

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Improving Health Care Access in Native American Communities: What Can Tribes Do

The research team will use case studies to examine the conditions under which tribal control is productive and those healthcare strategies that appear to be working. The projects eight case studies will focus on how healthcare strategies and access vary across different levels of tribal control among tribes in MI, MS, NM, and two additional states. The objective will be to characterize successful management strategies and to determine the role of tribal control and other key factors in their success.
Funder: W.K. Kellogg Foundation
Principal Investigator: Adams, Alyce

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Barriers to Adherence in Patients Prescribed a Statin

This study will examine patient-reported barriers to adherence to statin medication therapy and potential approaches for improving adherence among patients prescribed statins for primary prevention, secondary prevention, and coronary risk equivalents using structured telephone interviews in adult Kaiser Permanente Northern California members.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Jaffe, Marc

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Does primary stroke center certification change ED diagnosis, utilization, and disposition of patients with acute stroke?

Ballard, D. W.; Reed, M. E.; Huang, J.; Kramer, B. J.; Hsu, J.; Chettipally, U.;
 
Nov 17 2011
PubMed abstract  »

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Ethnic Differences in Appointment-Keeping and Implications for the Patient-Centered Medical Home-Findings from the Diabetes Study of Northern California (DISTANCE)

Parker, M. M.; Moffet, H. H.; Schillinger, D.; Adler, N.; Fernandez, A.; Ciechanowski, P.; Karter, A. J.;
 
Oct 27 2011
PubMed abstract  »

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The impact of maternal characteristics on the moderately premature infant: an antenatal maternal transport clinical prediction rule

Dukhovny, D.; Dukhovny, S.; Pursley, D. M.; Escobar, G. J.; McCormick, M. C.; Mao, W. Y.; Zupancic, J. A.;
 
Nov 10 2011
PubMed abstract  »

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Innovative policy strategies need empirical evaluation

Weisner, C.;
Addiction   106 (12): 2069-70
Dec 2011
PubMed abstract  »

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Adverse outcomes associated with delayed intensive care unit transfers in an integrated healthcare system

Liu, V.; Kipnis, P.; Rizk, N. W.; Escobar, G. J.;
 
Oct 28 2011
PubMed abstract  »

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Clinician awareness and knowledge of breast cancer-related lymphedema in a large, integrated health care delivery setting

Tam, E. K.; Shen, L.; Munneke, J. R.; Ackerson, L. M.; Partee, P. N.; Somkin, C. P.; Andre, M.; Kutner, S. E.; Thiadens, S. R.; Kwan, M. L.;
 
Oct 29 2011
PubMed abstract  »

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Predictors of recruited melanoma families into a behavioral intervention project

Bowen, D. J.; Hay, J. L.; Mayer, J.; Kuniyuki, A.; Meischke, H.; Harris, J.; Asgari, M.; Shoveller, J.; Press, N.; Burke, W.;
 
Oct 8 2011
PubMed abstract  »

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Continuing care and long-term substance use outcomes in managed care: early evidence for a primary care-based model

Chi, F. W.; Parthasarathy, S.; Mertens, J. R.; Weisner, C. M.;
  62 (10): 1194-200
Oct 2011
PubMed abstract  »

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Patient-Reported Racial/Ethnic Healthcare Provider Discrimination and Medication Intensification in the Diabetes Study of Northern California (DISTANCE)

Lyles, C. R.; Karter, A. J.; Young, B. A.; Spigner, C.; Grembowski, D.; Schillinger, D.; Adler, N.;
Journal of general internal medicine  26 (10): 1138-44
Oct 2011
PubMed abstract  »

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Patient-Reported Racial/Ethnic Healthcare Provider Discrimination and Medication Intensification in the Diabetes Study of Northern California (DISTANCE)

Lyles, C. R.; Karter, A. J.; Young, B. A.; Spigner, C.; Grembowski, D.; Schillinger, D.; Adler, N.;
  26 (10): 1138-44
Oct 2011
PubMed abstract  »

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Provision of Contraceptive Services to Women with Diabetes Mellitus

Schwarz, E. B.; Postlethwaite, D.; Hung, Y. Y.; Lantzman, E.; Armstrong, M. A.; Horberg, M. A.;
 
Sep 16 2011
PubMed abstract  »

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Provision of Contraceptive Services to Women with Diabetes Mellitus

Schwarz, E. B.; Postlethwaite, D.; Hung, Y. Y.; Lantzman, E.; Armstrong, M. A.; Horberg, M. A.;
Journal of general internal medicine 
Sep 16 2011
PubMed abstract  »

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Postacute care and ischemic stroke mortality: findings from an integrated health care system in northern california

Wang, H.; Sandel, M. E.; Terdiman, J.; Armstrong, M. A.; Klatsky, A.; Camicia, M.; Sidney, S.;
  3 (8): 686-94
Aug 2011
PubMed abstract  »

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Diagnosis, Comorbidities And Management Of Irritable Bowel Syndrome In Patients In A Large Health Maintenance Organization

Ladabaum, U.; Boyd, E.; Zhao, W. K.; Mannalithara, A.; Sharabidze, A.; Singh, G.; Chung, E.; Levin, T. R.;
 
Aug 23 2011
PubMed abstract  »

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Slowing demand for total joint arthroplasty in a population of 3.2 million

Bini, S. A.; Sidney, S.; Sorel, M.;
J Arthroplasty   26 (6 Suppl): 124-8
Sep 2011
PubMed abstract  »