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Research

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Health Disparities

Through such studies as The Diabetes Study of Northern California (DISTANCE), our researchers study the causes, the why and how, of disparities in health and health care. Their research contributes to the effort to minimize and eventually eliminate health disparities.

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Impact of Medicare Part D on Cancer and Diabetes Disparities Among Dual Enrollees

The purpose of this study is to investigate the impact of a major change in national health insurance coverage (the passage of Medicare Part D) on disparities in health services use, outcomes, and costs among vulnerable, chronically ill patients.
Funder: National Institute on Aging
Principal Investigator: Adams, Alyce

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Drug Cost Containment Changes and Quality of Care for Mentally Ill Dual Enrollees

This study will evaluate the impact of changes in drug cost containment policies associated with the shift from Medicaid to Part D drug coverage in four states (SC, MO, CA, NJ) among fee-for-service (non-managed care) dual enrollees with schizophrenia or bipolar disorder overall and in high risk subgroups (e.g., minorities).
Funder: Agency for Healthcare Research and Quality
Principal Investigator: Adams, Alyce

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Medication Adherence and Social Disparities in Diabetes

This study will evaluate whether diabetes, blood pressure, and cholesterol medications are taken by patients with diabetes as prescribed (“adherence”), emphasizing social patterns in adherence, clinical consequences, and reasons for differences in therapy initiation, maintenance, and discontinuation.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew

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The Impact of Language Concordance on the Health Care of Patients with Limited English Proficiency

This study characterize patient-provider language concordance/discordance, quality of care and health outcomes in diabetic patients with limited English proficiency.  We will also survey providers regarding their language fluency.
Funder: California Program on Access to Care
Principal Investigator: Karter, Andrew

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Diabetes, Social Disparities and Aging

This study focuses on diabetes-related care and outcomes among geriatric patients with diabetes. We will evaluate the effects of commonly used antihyperglycemic therapies, polypharmacy, hypoglycemia; geriatric syndromes, and quality of life; all-cause mortality, and explore the implications of the widespread adoption of geriatric diabetes guidelines for ethnic disparities in diabetes care.  
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew

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Adjuvant Breast Cancer Therapy: Race, Variation in Care and Survival

This study examines racial disparities in breast cancer prognosis, examining factors such as appropriate use of adjuvant therapy.
Funder: American Cancer Society
Principal Investigator: Kushi, Lawrence

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Physical and Social Environmental Factors in Adult Asthma

This study analyzes the cumulative risk of combined physical environmental and social environmental factors that affect asthma outcomes, giving particular emphasis to relationships that might be amenable to intervention/secondary-tertiary prevention strategies designed to improve outcomes.
Funder: Nat. Inst. of Environmental Health Sciences
Principal Investigator: Iribarren, Carlos

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Member Health Survey and Health Services Evaluation

This study provides information about the health status, health-related risks, needs and interests of adult health plan members.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Gordon, Nancy

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Surveillance Modeling of Racial Disparities in U.S. Prostate Cancer Trends

This study investigates what clinical factors contribute to observed/racial disparities in prostate cancer incidence and mortality.
Funder: National Cancer Institute
Principal Investigator: Van Den Eeden, Stephen

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Ethnic Disparities in Diabetes Complications

This study evaluates ethnic differences in the incidence and antecedents of diabetic complications in a large population of African-Americans, Asians, Caucasians, Filipinos and Latinos within an integrated managed care setting (Kaiser Permanente), and focuses on health services and epidemiologic aspects of diabetic complications, including myocardial infarction, stroke, congestive heart failure, end-stage renal disease, lower-extremity amputation and proliferative retinopathy.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew

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Educational Disparities in Diabetes Complications

This study evaluates the role of education in the incidence of diabetic complications in a large, well-characterized population within an integrated, managed care setting (Kaiser Permanente).
Funder: Nat. Inst. of Child Health and Human Dev.
Principal Investigator: Karter, Andrew

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Disparities in the risk of gestational diabetes by race-ethnicity and country of birth

Hedderson, M. M.; Darbinian, J. A.; Ferrara, A.;
Paediatr Perinat Epidemiol   24 (5): 441-8
Sep 2010
PubMed abstract »

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Gender Differences in Treatment of Severe Carotid Stenosis After Transient Ischemic Attack

Poisson, S. N.; Johnston, S. C.; Sidney, S.; Klingman, J. G.; Nguyen-Huynh, M. N.;
Stroke  
Jul 22 2010
PubMed abstract »

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Hemoglobin A1c between 5.7 and 6.4% as a marker for identifying pre-diabetes, insulin sensitivity and secretion, and cardiovascular risk factors: The Insulin Resistance Atherosclerosis Study (IRAS)

Lorenzo, C.; Wagenknecht, L. E.; Hanley, A. J.; Rewers, M. J.; Karter, A. J.; Haffner, S. M.;
Diabetes Care  
Jun 23 2010
PubMed abstract »

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Adherence to Cardiovascular Disease Medications: Does Patient-Provider Race/Ethnicity and Language Concordance Matter?

Traylor, A. H.; Schmittdiel, J. A.; Uratsu, C. S.; Mangione, C. M.; Subramanian, U.;
J Gen Intern Med  
Jun 23 2010
PubMed abstract »

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Dietary glycemic load, glycemic index, and associated factors in a multiethnic cohort of midlife women

Hu, Y.; Block, G.; Sternfeld, B.; Sowers, M.;
J Am Coll Nutr   28 (6): 636-47
Dec 2009
PubMed abstract »

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Hypoglycemia is More Common Among Type 2 Diabetes Patients with Limited Health Literacy: The Diabetes Study of Northern California (DISTANCE)

Sarkar, U.; Karter, A. J.; Liu, J. Y.; Moffet, H. H.; Adler, N. E.; Schillinger, D.;
J Gen Intern Med  
May 18 2010
PubMed abstract »

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Treatment of ductal carcinoma in situ among patients cared for in large integrated health plans

Haque, R.; Achacoso, N. S.; Fletcher, S. W.; Nekhlyudov, L.; Collins, L. C.; Schnitt, S. J.; Quesenberry, C. P., Jr.; Habel, L. A.;
Am J Manag Care   16 (5): 351-60
May 2010
PubMed abstract »

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Maternal and paternal race/ethnicity are both associated with gestational diabetes

Caughey, A. B.; Cheng, Y. W.; Stotland, N. E.; Washington, A. E.; Escobar, G. J.;
Am J Obstet Gynecol  
Apr 16 2010
PubMed abstract »

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Social disparities in dental insurance and annual dental visits among medically insured patients with diabetes: the Diabetes Study of Northern California (DISTANCE) Survey

Moffet, H. H.; Schillinger, D.; Weintraub, J. A.; Adler, N.; Liu, J. Y.; Selby, J. V.; Karter, A. J.;
Prev Chronic Dis  7 (3): 11
May 2010
PubMed abstract »

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Prevalence of electrocardiographic abnormalities in a middle-aged, biracial population: Coronary Artery Risk Development in Young Adults study

Walsh, J. A., 3rd; Prineas, R.; Daviglus, M. L.; Ning, H.; Liu, K.; Lewis, C. E.; Sidney, S.; Schreiner, P. J.; Iribarren, C.; Lloyd-Jones, D. M.;
J Electrocardiol  
Apr 5 2010
PubMed abstract »

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Race/Ethnicity, Social Support, and Associations With Diabetes Self-Care and Clinical Outcomes in NHANES

Rees, C. A.; Karter, A. J.; Young, B. A.;
Diabetes Educ  
Mar 23 2010
PubMed abstract »

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The impact of limited English proficiency and physician language concordance on reports of clinical interactions among patients with diabetes: The DISTANCE study

Schenker, Y.; Karter, A. J.; Schillinger, D.; Warton, E. M.; Adler, N. E.; Moffet, H. H.; Ahmed, A. T.; Fernandez, A.;
Patient Educ Couns  
Mar 9 2010
PubMed abstract »

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The predictors of patient-physician race and ethnic concordance: a medical facility fixed-effects approach

Traylor, A. H.; Schmittdiel, J. A.; Uratsu, C. S.; Mangione, C. M.; Subramanian, U.;
Health Serv Res  45 (3): 792-805
Jun 2010
PubMed abstract »

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Angiotensin-converting Enzyme-related Cough among Chinese-Americans

Tseng, D. S.; Kwong, J.; Rezvani, F.; Coates, A. O.;
Am J Med   123 (2): 183 e11-183 e15
Feb 2010
PubMed abstract »

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Chronic kidney disease in United States Hispanics: a growing public health problem

Lora, C. M.; Daviglus, M. L.; Kusek, J. W.; Porter, A.; Ricardo, A. C.; Go, A. S.; Lash, J. P.;
Ethn Dis   19 (4): 466-72
Autumn 2009
PubMed abstract »