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Research

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Health Disparities

Through such studies as The Diabetes Study of Northern California (DISTANCE), our researchers study the causes, the why and how, of disparities in health and health care. Their research contributes to the effort to minimize and eventually eliminate health disparities.

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Effective Care of Latinos with Diabetes and Limited English Proficiency

This study focuses on respondents from DISTANCE to determine if there is a differential impact of language concordant care on the outcomes of Latino patients with diabetes and limited English proficiency.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew

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Alameda County Network Program to Reduce Cancer Disparities

The goal of this project is to develop a Regional Center for Reducing Cancer Disparities through Outreach, Research and Training based in Alameda County, California, focusing on religion using Faith Based interventions that may be conducted in Faith Placed organizations.
Funder: National Cancer Institute
Principal Investigator: Somkin, Carol

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Improving Health Care Access in Native American Communities: What Can Tribes Do

The research team will use case studies to examine the conditions under which tribal control is productive and those healthcare strategies that appear to be working. The projects eight case studies will focus on how healthcare strategies and access vary across different levels of tribal control among tribes in MI, MS, NM, and two additional states. The objective will be to characterize successful management strategies and to determine the role of tribal control and other key factors in their success.
Funder: W.K. Kellogg Foundation
Principal Investigator: Adams, Alyce

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Enabling Minority Participation in Clinical Trials (EMPaCT)

To collaborate with investigators at UCD to determine barriers to clinical trials accrual among minorities and ways to mitigate those barriers.
Funder: National Cancer Institute
Principal Investigator: Somkin, Carol

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Impact of Medicare Part D on Cancer and Diabetes Disparities Among Dual Enrollees

The purpose of this study is to investigate the impact of a major change in national health insurance coverage (the passage of Medicare Part D) on disparities in health services use, outcomes, and costs among vulnerable, chronically ill patients.
Funder: National Institute on Aging
Principal Investigator: Adams, Alyce

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Effect of Race-ethnicity on Anti-Hypertensive Therapy and Blood Pressure Control in Patients with Ischemic Stroke

The specific aims of this study are to: 1) determine in the QUISP cohort the factors that could explain why African Americans have poorer blood pressure control compared to other races by examining potential barriers among patients with acute ischemic stroke in a large racially-diverse cohort, and 2) to determine to what extent failure to control blood pressure could account for the difference in 6 month post-stroke risk in recurrent stroke among the different races.
Funder: American Heart Association
Principal Investigator: Sidney, Stephen

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Drug Cost Containment Changes and Quality of Care for Mentally Ill Dual Enrollees

This study will evaluate the impact of changes in drug cost containment policies associated with the shift from Medicaid to Part D drug coverage in four states (SC, MO, CA, NJ) among fee-for-service (non-managed care) dual enrollees with schizophrenia or bipolar disorder overall and in high risk subgroups (e.g., minorities).
Funder: Agency for Healthcare Research and Quality
Principal Investigator: Adams, Alyce

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Medication Adherence and Social Disparities in Diabetes

This study will evaluate whether diabetes, blood pressure, and cholesterol medications are taken by patients with diabetes as prescribed (“adherence”), emphasizing social patterns in adherence, clinical consequences, and reasons for differences in therapy initiation, maintenance, and discontinuation.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew

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The Impact of Language Concordance on the Health Care of Patients with Limited English Proficiency

This study characterize patient-provider language concordance/discordance, quality of care and health outcomes in diabetic patients with limited English proficiency.  We will also survey providers regarding their language fluency.
Funder: California Program on Access to Care
Principal Investigator: Karter, Andrew

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Diabetes, Social Disparities and Aging

This study focuses on diabetes-related care and outcomes among geriatric patients with diabetes. We will evaluate the effects of commonly used antihyperglycemic therapies, polypharmacy, hypoglycemia; geriatric syndromes, and quality of life; all-cause mortality, and explore the implications of the widespread adoption of geriatric diabetes guidelines for ethnic disparities in diabetes care.  
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew

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Adjuvant Breast Cancer Therapy: Race, Variation in Care and Survival

This study examines racial disparities in breast cancer prognosis, examining factors such as appropriate use of adjuvant therapy.
Funder: American Cancer Society
Principal Investigator: Kushi, Lawrence

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Physical and Social Environmental Factors in Adult Asthma

This study analyzes the cumulative risk of combined physical environmental and social environmental factors that affect asthma outcomes, giving particular emphasis to relationships that might be amenable to intervention/secondary-tertiary prevention strategies designed to improve outcomes.
Funder: Nat. Inst. of Environmental Health Sciences
Principal Investigator: Iribarren, Carlos

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Member Health Survey and Health Services Evaluation

This study provides information about the health status, health-related risks, needs and interests of adult health plan members.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Gordon, Nancy

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Surveillance Modeling of Racial Disparities in U.S. Prostate Cancer Trends

This study investigates what clinical factors contribute to observed/racial disparities in prostate cancer incidence and mortality.
Funder: National Cancer Institute
Principal Investigator: Van Den Eeden, Stephen

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Ethnic Disparities in Diabetes Complications

This study evaluates ethnic differences in the incidence and antecedents of diabetic complications in a large population of African-Americans, Asians, Caucasians, Filipinos and Latinos within an integrated managed care setting (Kaiser Permanente), and focuses on health services and epidemiologic aspects of diabetic complications, including myocardial infarction, stroke, congestive heart failure, end-stage renal disease, lower-extremity amputation and proliferative retinopathy.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew

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Evaluating Racial/Ethnic Disparities in Lower Urinary Tract Symptoms in Men

Van Den Eeden, S. K.; Shan, J.; Jacobsen, S. J.; Aaronsen, D.; Haque, R.; Quinn, V. P.; Quesenberry, C. P., Jr.;
 
Nov 16 2011
PubMed abstract  »

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Ethnic Differences in Appointment-Keeping and Implications for the Patient-Centered Medical Home-Findings from the Diabetes Study of Northern California (DISTANCE)

Parker, M. M.; Moffet, H. H.; Schillinger, D.; Adler, N.; Fernandez, A.; Ciechanowski, P.; Karter, A. J.;
 
Oct 27 2011
PubMed abstract  »

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Ethnic differences in the development of albuminuria: the DISTANCE study

Choi, A. I.; Karter, A. J.; Liu, J. Y.; Young, B. A.; Go, A. S.; Schillinger, D.;
  17 (11): 737-745
Nov 2011
PubMed abstract  »

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The Relationship Between Neighborhood Characteristics and Recruitment into Adolescent Family-Based Substance Use Prevention Programs

Byrnes, H. F.; Miller, B. A.; Aalborg, A. E.; Keagy, C. D.;
 
Oct 29 2011
PubMed abstract  »

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Patient-Reported Racial/Ethnic Healthcare Provider Discrimination and Medication Intensification in the Diabetes Study of Northern California (DISTANCE)

Lyles, C. R.; Karter, A. J.; Young, B. A.; Spigner, C.; Grembowski, D.; Schillinger, D.; Adler, N.;
Journal of general internal medicine  26 (10): 1138-44
Oct 2011
PubMed abstract  »

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Patient-Reported Racial/Ethnic Healthcare Provider Discrimination and Medication Intensification in the Diabetes Study of Northern California (DISTANCE)

Lyles, C. R.; Karter, A. J.; Young, B. A.; Spigner, C.; Grembowski, D.; Schillinger, D.; Adler, N.;
  26 (10): 1138-44
Oct 2011
PubMed abstract  »

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Formal and informal substance use treatment utilization and alcohol abstinence over seven years: Is the relationship different for blacks and whites?

Avalos, L. A.; Mulia, N.;
Drug and alcohol dependence 
Sep 20 2011
PubMed abstract  »

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Formal and informal substance use treatment utilization and alcohol abstinence over seven years: Is the relationship different for blacks and whites?

Avalos, L. A.; Mulia, N.;
 
Sep 20 2011
PubMed abstract  »

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Racial/ethnic differences in initiation of adjuvant hormonal therapy among women with hormone receptor-positive breast cancer

Livaudais, J. C.; Hershman, D. L.; Habel, L.; Kushi, L.; Gomez, S. L.; Li, C. I.; Neugut, A. I.; Fehrenbacher, L.; Thompson, B.; Coronado, G. D.;
 
Sep 16 2011
PubMed abstract  »

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Racial/ethnic differences in initiation of adjuvant hormonal therapy among women with hormone receptor-positive breast cancer

Livaudais, J. C.; Hershman, D. L.; Habel, L.; Kushi, L.; Gomez, S. L.; Li, C. I.; Neugut, A. I.; Fehrenbacher, L.; Thompson, B.; Coronado, G. D.;
Breast cancer research and treatment 
Sep 16 2011
PubMed abstract  »

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Cardiovascular Disease Among Hispanics and Non-Hispanics in the Chronic Renal Insufficiency Cohort (CRIC) Study

Ricardo, A. C.; Lash, J. P.; Fischer, M. J.; Lora, C. M.; Budoff, M.; Keane, M. G.; Kusek, J. W.; Martinez, M.; Nessel, L.; Stamos, T.; Ojo, A.; Rahman, M.; Soliman, E. Z.; Yang, W.; Feldman, H. I.; Go, A. S.;
  6 (9): 2121-2131
Sep 2011
PubMed abstract  »

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A case-control study of asphalt and tar exposure and lung cancer in minorities

McClean, M. D.; Kelsey, K. T.; Sison, J. D.; Quesenberry, C. P., Jr.; Wrensch, M. R.; Wiencke, J. K.;
 
Aug 31 2011
PubMed abstract  »

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Racial and ethnic differences in the prevalence of placenta previa

Kim, L. H.; Caughey, A. B.; Laguardia, J. C.; Escobar, G. J.;
 
Jun 30 2011
PubMed abstract  »

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Racial and ethnic differences in the prevalence of placenta previa

Kim, L. H.; Caughey, A. B.; Laguardia, J. C.; Escobar, G. J.;
Journal of perinatology : official journal of the California Perinatal Association 
Jun 30 2011
PubMed abstract  »

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CKD in Hispanics: Baseline characteristics from the CRIC (Chronic Renal Insufficiency Cohort) and Hispanic-CRIC Studies

Fischer, M. J.; Go, A. S.; Lora, C. M.; Ackerson, L.; Cohan, J.; Kusek, J. W.; Mercado, A.; Ojo, A.; Ricardo, A. C.; Rosen, L. K.; Tao, K.; Xie, D.; Feldman, H. I.; Lash, J. P.;
American journal of kidney diseases : the official journal of the National Kidney Foundation  58 (2): 214-27
Aug 2011
PubMed abstract  »