Retrospective Assessment of Military Occupations & Neurodegenerative Disease
The specific aims of this project are: (1) to develop exposure assessment methodology for collecting objective information about military occupations and exposures, and (2) to apply the newly developed methodology to determine whether military service is associated with ALS and PD in three completed population-based case-control studies conducted in Northern California and Western Washington State.
Funder: Nat. Inst. for Occupational Safety and Health
Principal Investigator: Van Den Eeden, Stephen
Genes-Environments and Admixture in Latino Asthmatics (GALA-2)
Funder: Sandler Family Foundation
Principal Investigator: Brigino-Buenaventura, Emerita
Environment, the Perinatal Epigenome and Risk for Autism and Related Disorders
This goal of this study is to understand the relationship between environmental exposures, epigenetics, and risk for autism. Our proposal will address four main themes: (1) the effects of pre and perinatal exposures on genome-wide methylation in mother, father, and child, (2) the familiality of DNAm and DNAm changes, (3) the effects of DNAm on child development and autism risk, and (4) the integration of GWAS SNP and CNV data already funded for this project with these epigenetic data to capture genetic and epigenetic effects in the epidemiology of autism.
Funder: National Cancer Institute
Principal Investigator: Croen, Lisa
Neighborhood Effects on Weight and Diabetes Complications
We propose to evaluate hypothesized relationships between neighborhood-level influences on diabetes self-care, cardiometabolic markers of disease and health outcomes by studying patients with diabetes and uniform access to health care.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew
SEER Special Study: Improving Understanding of Breast Cancer Health Disparities Using Linked Data Sets
The aim of this study is to 1) compare treatment patterns and receipt among National Comprehensive Cancer Network guidelines among breast cancer patients from 1998 to 2008 by race/ethnicity and neighborhood socio-economic status 2) compare breast cancer subtype by neighborhood socio-economic status and race ethncicity 3) compare the extent of adherence to guideline treatment by neighborhood socio-economic status 4) examine impact of neighborhood socio-economic status, and access factors, breast cancer subtype and adherence to guidline treatment on breast cancer survival.
Funder: Health Resources and Services
Principal Investigator: Caan, Bette
Maternal and Infant Genetic Contributions to Preterm Birth: the Inflammatory Response
This study examines how prenatal exposure to environmental triggers is associated with premature birth as mediated by individual expression of host metabolites and examination of the potential interaction of prenatal environmental exposures and genetic variation in the expression of inflammatory response regulation in relation to premature birth.
Funder: March of Dimes
Principal Investigator: DeLorenze, Gerald
Epidemiology of Dystonia in a Multi-ethnic Population
This study addresses the three major deficiencies in the current understanding of Primary Torsion Dystonia (PTD) based on incidence on a multi-ethnic population, examining the distribution of genetic determinants, and investigating environmental factors affecting disease expression on risk.
Funder: Nat. Inst. of Neurological Disorders and Stroke
Principal Investigator: Van Den Eeden, Stephen
A case-control study of asphalt and tar exposure and lung cancer in
minorities
McClean, M. D.;
Kelsey, K. T.;
Sison, J. D.;
Quesenberry, C. P., Jr.;
Wrensch, M. R.;
Wiencke, J. K.;
Aug 31 2011
PubMed abstract
»
Prenatal exposure to beta2-adrenergic receptor agonists and risk of
autism spectrum disorders
Croen, L. A.;
Connors, S. L.;
Matevia, M.;
Qian, Y.;
Newschaffer, C.;
Zimmerman, A. W.;
Journal of neurodevelopmental disorders
Aug 27 2011
PubMed abstract
»
Maternal Exposure to Magnetic Fields During Pregnancy in Relation
to the Risk of Asthma in Offspring
Li, D. K.;
Chen, H.;
Odouli, R.;
Arch Pediatr Adolesc Med
Aug 1 2011
PubMed abstract
»
Genetic Heritability and Shared Environmental Factors Among Twin
Pairs With Autism
Hallmayer, J.;
Cleveland, S.;
Torres, A.;
Phillips, J.;
Cohen, B.;
Torigoe, T.;
Miller, J.;
Fedele, A.;
Collins, J.;
Smith, K.;
Lotspeich, L.;
Croen, L. A.;
Ozonoff, S.;
Lajonchere, C.;
Grether, J. K.;
Risch, N.;
Arch Gen Psychiatry
Jul 4 2011
PubMed abstract
»
In utero exposure to bisphenol-A and its effect on birth weight of
offspring
Miao, M.;
Yuan, W.;
Zhu, G.;
He, X.;
Li, D. K.;
32
(1):
64-8
Jul 2011
PubMed abstract
»
Polychlorinated biphenyl (PCB) exposure in mothers and time to
pregnancy in daughters
Cohn, B. A.;
Cirillo, P. M.;
Sholtz, R. I.;
Ferrara, A.;
Park, J. S.;
Schwingl, P. J.;
Reprod Toxicol
Feb 2 2011
PubMed abstract
»
Urine bisphenol-A (BPA) level in relation to semen quality
Li, D. K.;
Zhou, Z.;
Miao, M.;
He, Y.;
Wang, J.;
Ferber, J.;
Herrinton, L. J.;
Gao, E.;
Yuan, W.;
Fertil Steril
95
(2):
625-30 e1-4
Feb 2011
PubMed abstract
»
Relationship between urine bisphenol-A level and declining male sexual function
Li, D. K.;
Zhou, Z.;
Miao, M.;
He, Y.;
Qing, D.;
Wu, T.;
Wang, J.;
Weng, X.;
Ferber, J.;
Herrinton, L. J.;
Zhu, Q.;
Gao, E.;
Yuan, W.;
J Androl
31
(5):
500-6
Sep-Oct 2010
PubMed abstract
»
Ambient Ozone Concentrations and Cardiac Mortality in Southern
California 1983-2000: Application of a New Marginal Structural
Model Approach
Moore, K.;
Neugebauer, R.;
Lurmann, F.;
Hall, J.;
Brajer, V.;
Alcorn, S.;
Tager, I.;
Am J Epidemiol
May 3 2010
PubMed abstract
»
Investigation of Relationships between Urinary Biomarkers of Phytoestrogens, Phthalates, and Phenols and Pubertal Stages in Girls
Wolff, M. S.;
Teitelbaum, S. L.;
Pinney, S. M.;
Windham, G.;
Liao, L.;
Biro, F.;
Kushi, L. H.;
Erdmann, C.;
Hiatt, R. A.;
Rybak, M. E.;
Calafat, A. M.;
Environ Health Perspect
118
(7):
1039-46
Jul 2010
PubMed abstract
»
Body burdens of brominated flame retardants and other persistent
organo-halogenated compounds and their descriptors in US girls
Windham, G. C.;
Pinney, S. M.;
Sjodin, A.;
Lum, R.;
Jones, R. S.;
Needham, L. L.;
Biro, F. M.;
Hiatt, R. A.;
Kushi, L. H.;
Environ Res
Feb 1 2010
PubMed abstract
»
Passive Smoke Exposure and Circulating Carotenoids in the CARDIA
Study
Widome, R.;
Jacobs, D. R., Jr.;
Hozawa, A.;
Sijtsma, F.;
Gross, M.;
Schreiner, P. J.;
Iribarren, C.;
Ann Nutr Metab
56
(2):
113-118
Jan 29 2010
PubMed abstract
»
Exposure to magnetic fields and the risk of poor sperm quality
Li, D. K.;
Yan, B.;
Li, Z.;
Gao, E.;
Miao, M.;
Gong, D.;
Weng, X.;
Ferber, J. R.;
Yuan, W.;
Reprod Toxicol
29
(1):
86-92
Jan 2010
PubMed abstract
»
Occupational exposure to bisphenol-A (BPA) and the risk of self-reported male sexual dysfunction
Li, D.;
Zhou, Z.;
Qing, D.;
He, Y.;
Wu, T.;
Miao, M.;
Wang, J.;
Weng, X.;
Ferber, J. R.;
Herrinton, L. J.;
Zhu, Q.;
Gao, E.;
Checkoway, H.;
Yuan, W.;
Hum Reprod
25
(2):
519-27
Feb 2010
PubMed abstract
»
Occupational exposure levels of bisphenol A among Chinese workers
He, Y.;
Miao, M.;
Wu, C.;
Yuan, W.;
Gao, E.;
Zhou, Z.;
Li, D. K.;
J Occup Health
51
(5):
432-6
2009
PubMed abstract
»