Project to Reduce Over-Medication of the Elderly (PROMOTE)
This is an observation study looking at the prevalence of inappropriate medication use and association with certain patient characteristics and adverse outcomes in a cohort of elderly homebound Kaiser Permanente members.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Mui, Silbey
Diabetes, Social Disparities and Aging
This study focuses on diabetes-related care and outcomes among geriatric patients with diabetes. We will evaluate the effects of commonly used antihyperglycemic therapies, polypharmacy, hypoglycemia; geriatric syndromes, and quality of life; all-cause mortality, and explore the implications of the widespread adoption of geriatric diabetes guidelines for ethnic disparities in diabetes care.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Karter, Andrew
Prophylactic Oophorectomy: Practice Patterns and Outcomes
This study aims to estimate the secular trends of prophylactic salpingo-oophorectomy by patient characteristics, examine practice patterns of prophylactic salpingo-oophorectomy by surgeon characteristics, and to estimate the risk of subsequent adnexal surgery after ovarian preservation.
Funder: National Institute on Aging
Principal Investigator: Habel, Laurel
Sex Hormones, Related Polymorphisms and Cognitive Decline
This study seeks to ascertain the role of hormone replacement therapy in midlife on risk of dementia.
Funder: National Institute on Aging
Principal Investigator: Whitmer, Rachel
Epidemiology of Glycemia, Inflammation and Cognition
The goal of this study is to determine the association of measures of glycemia and insulinemia with cognitive functioning.
Funder: Nat. Inst.of Diabetes & Digestive & Kidney Disease
Principal Investigator: Whitmer, Rachel
Midlife Respiratory Function and Risk of Dementia
This study evaluates the association between midlife respiratory function and risk of dementia more than two decades later. A secondary aim is to ascertain how the association between respiratory function and dementia risk may vary by smoking status.
Funder: Kaiser Permanente Community Benefit Program
Principal Investigator: Whitmer, Rachel
ALIVE (A Lifestyle Intervention Via Email) for Older Workers
This study aims to modify the ALIVE program to make it more relevant for workers ages 55 to 64, and to test the efficacy of the modified version in a randomized trial that also includes an evaluation of adding printed intervention materials to the messages delivered by email.
Funder: National Institute on Aging
Principal Investigator: Sternfeld, Barbara
Obesity, Adipocytokines and Cognitive Aging
This project examines the associations between overall obesity, visceral obesity, leptin, adiponectin and levels of cognitive functioning, as well as cognitive decline in a cohort of elderly community-dwelling Latinos.
Funder: National Institute on Aging
Principal Investigator: Whitmer, Rachel
Center on Applied Genetic and Epidemiologic Research on Aging
This project helped to fund the development of the Research Program on Genes, Environment and Health through support of a mailed survey of adult Kaiser Permanente Northern California members and development of computerized disease registries.
Funder: Ellison Medical Foundation
Principal Investigator: Schaefer, Catherine
Assessing the Potential for Angiotensin Receptor Blockers in Prevention and Treatment of Dementia
This project aims to investigate whether angiotensin receptor blockers are associated with a reduced risk of dementia, as well as dementia progression and death in two independent data sets.
Funder: National Heart, Lung, and Blood Institute
Principal Investigator: Whitmer, Rachel
A characterization of the relationship of ovarian reserve markers
with age
Rosen, M. P.;
Johnstone, E.;
McCulloch, C. E.;
Schuh-Huerta, S. M.;
Sternfeld, B.;
Reijo-Pera, R. A.;
Cedars, M. I.;
Nov 29 2011
PubMed abstract
»
Bone and the perimenopause
Lo, J. C.;
Burnett-Bowie, S. A.;
Finkelstein, J. S.;
38
(3):
503-17
Sep 2011
PubMed abstract
»
Physical activity and health during the menopausal transition
Sternfeld, B.;
Dugan, S.;
38
(3):
537-66
Sep 2011
PubMed abstract
»
Physical activity and health during the menopausal transition
Sternfeld, B.;
Dugan, S.;
Obstetrics and gynecology clinics of North America
38
(3):
537-66
Sep 2011
PubMed abstract
»
Bone and the perimenopause
Lo, J. C.;
Burnett-Bowie, S. A.;
Finkelstein, J. S.;
Obstetrics and gynecology clinics of North America
38
(3):
503-17
Sep 2011
PubMed abstract
»
Are vasomotor symptoms associated with alterations in hemostatic
and inflammatory markers? Findings from the Study of Women's Health
Across the Nation
Thurston, R. C.;
El Khoudary, S. R.;
Sutton-Tyrrell, K.;
Crandall, C. J.;
Gold, E.;
Sternfeld, B.;
Selzer, F.;
Matthews, K. A.;
Menopause
Sep 15 2011
PubMed abstract
»
Are vasomotor symptoms associated with alterations in hemostatic
and inflammatory markers? Findings from the Study of Women's Health
Across the Nation
Thurston, R. C.;
El Khoudary, S. R.;
Sutton-Tyrrell, K.;
Crandall, C. J.;
Gold, E.;
Sternfeld, B.;
Selzer, F.;
Matthews, K. A.;
Menopause
Sep 15 2011
PubMed abstract
»
Patterns of alcohol and drug use among depressed older adults
seeking outpatient psychiatric services
Satre, D. D.;
Sterling, S. A.;
Mackin, R. S.;
Weisner, C.;
Am J Geriatr Psychiatry
19
(8):
695-703
Aug 2011
PubMed abstract
»
Reproductive and menstrual factors and risk of ductal carcinoma in
situ of the breast in a cohort of postmenopausal women
Kabat, G. C.;
Kim, M. Y.;
Woods, N. F.;
Habel, L. A.;
Messina, C. R.;
Wactawski-Wende, J.;
Stefanick, M. L.;
Chlebowski, R. T.;
Wassertheil-Smoller, S.;
Rohan, T. E.;
Cancer Causes Control
Jul 13 2011
PubMed abstract
»
Physical Activity in Older Subjects Is Associated With Increased Coronary Vasodilation The ADVANCE Study
Nguyen, P. K.;
Terashima, M.;
Fair, J. M.;
Varady, A.;
Taylor-Piliae, R. E.;
Iribarren, C.;
Go, A. S.;
Haskell, W. L.;
Hlatky, M. A.;
Fortmann, S. P.;
McConnell, M. V.;
JACC Cardiovasc Imaging
4
(6):
622-9
Jun 2011
PubMed abstract
»
Correlates of Quality-of-Life in Older Adults With Diabetes: The Diabetes & Aging Study
Laiteerapong, N.;
Karter, A. J.;
Liu, J. Y.;
Moffet, H. H.;
Sudore, R.;
Schillinger, D.;
John, P. M.;
Huang, E. S.;
Diabetes Care
Jun 2 2011
PubMed abstract
»
Oral health considerations in older women receiving oral bisphosphonate therapy
Lo, J. C.;
O'Ryan, F.;
Yang, J.;
Hararah, M. K.;
Gonzalez, J. R.;
Gordon, N.;
Silver, P.;
Ansfield, A.;
Wang, B.;
Go, A. S.;
J Am Geriatr Soc
59
(5):
916-22
May 2011
PubMed abstract
»
Timing of hormone therapy and dementia: the critical window theory
revisited
Whitmer, R. A.;
Quesenberry, C. P.;
Zhou, J.;
Yaffe, K.;
Ann Neurol
69
(1):
163-9
Jan 2011
PubMed abstract
»
Efficacy of escitalopram for hot flashes in healthy menopausal
women: a randomized controlled trial
Freeman, E. W.;
Guthrie, K. A.;
Caan, B.;
Sternfeld, B.;
Cohen, L. S.;
Joffe, H.;
Carpenter, J. S.;
Anderson, G. L.;
Larson, J. C.;
Ensrud, K. E.;
Reed, S. D.;
Newton, K. M.;
Sherman, S.;
Sammel, M. D.;
LaCroix, A. Z.;
JAMA
305
(3):
267-74
Jan 19 2011
PubMed abstract
»
Metabolic syndrome and mammographic density: The study of women's
health across the nation (SWAN)
Conroy, S. M.;
Butler, L. M.;
Harvey, D.;
Gold, E. B.;
Sternfeld, B.;
Greendale, G. A.;
Habel, L. A.;
Int J Cancer
Nov 23 2010
PubMed abstract
»