Obesity in Ovarian Cancer Prognosis
The research project aims to examine the association of weight and weight change on ovarian cancer survival and CA-125 levels, a tumor marker used routinely in the clinical management of ovarian cancer.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence
CRN Pilot: Cancer Risk Factors for Young Adults
For this one-year pilot study, the two data-contributing sites we will identify eligible active members of the health plan beginning 1/1/2007 who are 20-39 years old. Each site will obtain IRB approval and Data Use Agreements, and prepare programs to meet the specific aims of the pilot study: 1) to describe the completeness of data on risk factors, confounders and effect modifiers to study the association between obesity, diabetes, metabolic syndrome and common cancers in young adults at KP Southern and Northern California, and 2) to build a prospective cohort of young adults to investigate risk factors in the young adults which will serve as a potential CRN resource for other seeking to collaborate on studies.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence
Effects of Antioxidant Supplementation During Adjuvant Therapy for Breast Cancer
Career Development Award for developing Heather Greenlee, ND, PhDs expertise in the safety and efficacy of antioxidant supplement use during breast cancer adjuvant therapy.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence
Mammary Gland Evaluation and Risk Assessment
The goal of this study is to develop and publish standardized protocols for evaluating effects of developmental exposures on mammary gland development.
Funder: California Breast Cancer Research Program
Principal Investigator: Kushi, Lawrence
Genetics of Tamoxifen Response
The goal of this project is to improve our understanding of genetic factors that alter Tamoxifen responsiveness.
Funder: California Breast Cancer Research Program
Principal Investigator: Kushi, Lawrence
Comparative Effectiveness in Genomic & Personalized Medicine for Colon Cancer
This project has a major focus on genetic testing in colorectal cancer.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence
Building CER Capacity: Aligning CRN, CMS, and State Resources to Map Center Care
This is a project to develop capacity to examine patterns of care and outcomes, across data derived from selected CRN sites (KPNC, KPNW, KPCO, KPGA, GHC), SEER-Medicare, Medicaid, and the National Comprehensive Cancer Network.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence
Prospective Study of Breast Cancer Survivorship
Prospective Study of Breast Cancer Survivorship
Funder: Kaiser Foundation Research Institute
Principal Investigator: Kushi, Lawrence
Adjuvant Breast Cancer Therapy: Race, Variation in Care and Survival
This study examines racial disparities in breast cancer prognosis, examining factors such as appropriate use of adjuvant therapy.
Funder: American Cancer Society
Principal Investigator: Kushi, Lawrence
Using Physiological Age to Predict Chemotherapy Toxicity
This application builds upon the NCI-funded prospective cohort study of breast cancer survivorship, and examines the effects of functional status and physiologic age on effectiveness of chemotherapy.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence
Neighborhoods and Obesity in Preadolescent Girls: Part II
This project investigates how city planning policies and the neighborhood environment affect physical activity and diet behaviors of seven-year-old girls already participating in a longitudinal observational study about the predictors of pubertal transition.
Funder: California Breast Cancer Research Program
Principal Investigator: Kushi, Lawrence
CRN III: Cancer Research Network Across Health Care Systems
This is a collaboration on infrastructure-related activities of the Cancer Research Network. This includes participation in data exploration efforts to support new research projects, support for pilot projects, and other activities related to supporting cancer research in the HMO setting.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence
Racial Disparities in Optimal Receipt and Compliance With Adjuvant Breast Cancer Therapies: Behavioral, Communications, Biological, Economic, Psychosocial and Toxicity related Factors
This is a study of the biological, toxicity-related, behavioral, communication, economic, psycho-social, cultural, and molecular genetic factors that can contribute to racial disparities in the referral, receipt, adherence and response to systemic adjuvant breast cancer therapy.
Funder: Department of Defense
Principal Investigator: Kushi, Lawrence
Prospective Study of Breast Cancer Survivorship
This project establishes the largest prospective cohort study of women with breast cancer to date and examines associations of lifestyle factors and molecular markers on risk of recurrence and mortality.
Funder: National Cancer Institute
Principal Investigator: Kushi, Lawrence
The Bay Area Breast Cancer and the Environment Research Center
This project creates a cooperative network of breast cancer research centers in which multidisciplinary teams work collaboratively on a unique set of scientific questions that focus on how chemical, physical, biological and social factors in the environment work together with genetic factors to cause breast cancer.
Funder: Nat. Inst. of Environmental Health Sciences
Principal Investigator: Kushi, Lawrence